Neuroscience and Physiology
A central goal of life sciences research has been to understand how complex tissues and their substituent cells develop, function, and regenerate. Recent years have brought enormous advances in our ability to experimentally manipulate gene expression in cells, embryos, and tissues, and to analyze subtle and complex phenotypes using advanced imaging technologies.
The Neuroscience and Physiology Research Area brings together laboratories employing these technological advances to study the development, structure, function, and regeneration of the nervous system, as well as the functional and mechanistic basis of a broad range of fundamental behaviors such as vision, hearing, movement, learning, and social interactions in a wide variety of taxa.
- Our members bring the tools of molecular and cellular biology, advanced light microscopy, electrophysiology, transgenesis, mutagenesis, experimental embryology, behavior assessment and analysis to bear on these problems.
- We combine these tools with the power of several model systems including zebrafish, mouse, rat, Drosophila, and Aplysia.
- In addition to studying the development and function of the nervous system, several groups also investigate neurological disorders, including blindness, deafness, neurodegenerative diseases, autism and musculoskeletal disorders.
- One of the strengths of our group is the multiple approaches and techniques used to answer important questions at the genetic, cellular, physiological, and organismal levels.
The group provides interdisciplinary training in a collaborative environment for undergraduates, graduate students, and postdoctoral fellows. Resources and opportunities for collaboration are provided to the group through the Purdue Institute for Integrative Neuroscience, PHASE (Purdue Hearing & Acoustics in Science & Engineering), the Bindley Bioscience Center, the Birck Nanotechnology Center, the Genomics Center, and numerous colleges and departments across Purdue, particularly Biomedical Engineering and Medicinal Chemistry and Molecular Pharmacology.
Our research is supported by grants from the NIH, the NSF, and other extramural and intramural funding agencies.
Neuroscience and Physiology News
- Common genetic variants link autism, ADHD, and Tourette syndrome
- Contrary to a long-held belief, zebrafish larvae can see with their rod photoreceptors
- Collaborative effort by the Suter, Mattoo, and Huang labs provide new insights into filopodia formation
- New quantum material could warn of neurological disease
- Making sense of large-scale behavioural data for eye-drug discovery
- Chubykin Led Research Team that Develop New Robotic System to Study Brain