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85% Biological Sciences, 15% Biomedical Engineering
  • 765-496-2235
  • Discovery Learning Research 433


(Structural Biology and Biophysics) Macromolecular structure and function using diffraction and cryo-EM. Enzyme mechanisms, protein-protein and protein-ligand interactions.


The laboratory has a long term interest in understanding the relationship between atomic resolution structures and molecular function. We use X-ray crystallography and electron cryo-microscopy as the primary structure determination tools. We are interested in a wide variety of enzymes and membrane transporters, from both a basic biology perspective as well in their relevance to disease and applications. A major factor that drives the labs research is curiosity and our work on ‘cockroach milk’ and ‘blue fish’ are popular examples. There are two threads that run through the labs research program. The first one is on being sweet (sugars, especially nine carbon sugars) and the second metal (Fe/Zn) enzymes.


PhD Molecular Biophysics, Indian Institute of Science, 1992.

Previous Positions

  • Senior Professor and Dean, Institute for Stem Cell Science and Regenerative Biology, Bangalore, India.
  • CEO and co-founder, Center for Cellular and Molecular Platforms.

Other Activities

  • Connecting discovery to innovation.
  • Bridging the gap between availability and accessibility of technologies in research.
  • Entrepreneurship.

List of publications on Google Scholar

Ramaswamy Subramanian at TEDxMAIS

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