Bing YangAssistant Professor765-494-4130 HANS327A yang3099@purdue.edu Associated website(s): |
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PROFESSIONAL FACULTY RESEARCH
miRNA biogenesis; Microprocessor; CRISPR screens; intrinsic disorder regions; liquid-liquid phase separation; biomolecular condensates
BIO
Bing Yang is a molecular geneticist whose research focuses on understanding the mechanisms of miRNA biogenesis and characterizing the formation and function of biomolecular condensates formed by miRNA biogenesis machineries. Her work employs techniques including proteomics, genome editing, super-resolution microscopy, RNA biochemistry, and RNA secondary/tertiary structure probing and modeling.
Education
B.S. in Biology, Wuhan University, 2011
Ph.D. in Biology, Syracuse University, 2018
Postdoc at the National Institutes of Health, 2018-2025
Selected Publications
B. Yang , B. Galletta, R. Sakhawala, N. Rusan, K. McJunkin. (2025) An intrinsically disordered region of Drosha selectively promotes miRNA biogenesis, independent of tissue-specific Microprocessor condensates. Genes & Development. In Press.
B. Yang , M. Schwartz, K. McJunkin. (2020) In vivo CRISPR screening for phenotypic targets of the mir-35-42 family in C. elegans. Genes & Development 34:1227-1238.
B. Yang , K. McJunkin. (2020) CRISPR screening strategies for microRNA target identification. FEBS J 287:2914-2922.
B. Yang , K. McJunkin. (2020) The mir-35-42 binding site in the nhl-2 3’UTR is dispensable for development and fecundity. Micropublication Biology.
B. Yang , X. Xu, L. Russell, M. Sullenberger, J. Yanowitz and E. M. Maine. (2019) A DNA repair protein and histone methyltransferase interact to promote genome stability in the Caenorhabditis elegans germ line. PLOS Genetics 15(2):e1007992.