Shijie Wang

Shijie Wang, Ph.D., is an Altos Labs Postdoctoral Fellow in Steven Finkbeiner’s lab at the Gladstone Institutes and the University of California, San Francisco. Her research asks how individual human neurons change on the path to neurodegeneration, and how to detect those changes early enough to intervene. She builds human disease models from iPSC-derived neurons and studies them with automated longitudinal microscopy, CRISPR screens, and engineered biosensors, using deep learning to find the earliest signs of disease. She is a member of the Thinking Microscope team, which is building a closed-loop platform that observes, reasons, and perturbs living cells to test cause and effect. Her long-term goal is to build AI-guided imaging systems that reveal disease mechanisms invisible to conventional approaches.