Publications

ORCID: https://orcid.org/0000-0002-9254-9951

PubMed: https://www.ncbi.nlm.nih.gov/myncbi/qing.deng.1/bibliography/42120085/public/

 

2020:

Editorial: The Function of Phagocytes in Non-Mammals.

Lu XJ, Deng Q, Thompson KD.

Front Immunol. 2020 Dec 11;11:628847. doi: 10.3389/fimmu.2020.628847. eCollection 2020.

 

Mitofusin 2 regulates neutrophil adhesive migration and the actin cytoskeleton.

Zhou W, Hsu AY, Wang Y, Syahirah R, Wang T, Jeffries J, Wang X, Mohammad H, Seleem MN, Umulis D, Deng Q.

J Cell Sci. 2020 Sep 4;133(17):jcs248880. doi: 10.1242/jcs.248880.


Discovery of Small Molecules That Target the Phosphatidylinositol (3,4,5) Trisphosphate (PIP3)-Dependent Rac Exchanger 1 (P-Rex1) PIP3-Binding Site and Inhibit P-Rex1-Dependent Functions in Neutrophils.

Cash JN, Chandan NR, Hsu AY, Sharma PV, Deng Q, Smrcka AV, Tesmer JJG.

Mol Pharmacol. 2020 Mar;97(3):226-236. doi: 10.1124/mol.119.117556. Epub 2020 Jan 3.PMID: 31900312

2019:

Phenotypical microRNA screen reveals a noncanonical role of CDK2 in regulating neutrophil migration.

Hsu AY, Wang D, Liu S, Lu J, Syahirah R, Bennin DA, Huttenlocher A, Umulis DM, Wan J, Deng Q.

Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18561-18570. doi: 10.1073/pnas.1905221116. Epub 2019 Aug 26.

Inducible overexpression of zebrafish microRNA-722 suppresses chemotaxis of human neutrophil like cells.
Hsu AY, Liu S, Syahirah R, Brasseale KA, Wan J, Deng Q.
Mol Immunol. 2019 Aug;112:206-214. doi: 10.1016/j.molimm.2019.06.001. Epub 2019 Jun 5.

miRNA-223 at the crossroads of inflammation and cancer.
Jeffries J, Zhou W, Hsu AY, Deng Q.
Cancer Lett. 2019 Jun 1;451:136-141. doi: 10.1016/j.canlet.2019.02.051. Epub 2019 Mar 13.

  

2018:

nox2/cybb Deficiency Affects Zebrafish Retinotectal Connectivity.
Weaver CJ, Terzi A, Roeder H, Gurol T, Deng Q, Leung YF, Suter DM.
J Neurosci. 2018 Jun 27;38(26):5854-5871. doi: 10.1523/JNEUROSCI.1483-16.2018

Development and Characterization of an Endotoxemia Model in Zebra Fish.
Hsu AY, Gurol T, Sobreira TJP, Zhang S, Moore N, Cai C, Zhang ZY, Deng Q.
Front Immunol. 2018 Mar 29;9:607. doi: 10.3389/fimmu.2018.00607. eCollection 2018.

Neutrophil-specific knockout demonstrates a role for mitochondria in regulating neutrophil motility in zebrafish.
Zhou W, Cao L, Jeffries J, Zhu X, Staiger CJ, Deng Q.
Dis Model Mech. 2018 Mar 28;11(3).

MicroRNA-223 Suppresses the Canonical NF-κB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation.
Zhou W, Pal AS, Hsu AY, Gurol T, Zhu X, Wirbisky-Hershberger SE, Freeman JL, Kasinski AL, Deng Q.
Cell reports. 2018; 22(7):1810-1823.

 

2017:

Overexpression of microRNA-722 fine-tunes neutrophilic inflammation by inhibiting Rac2 in zebrafish.
Hsu AY, Wang D, Gurol T, Zhou W, Zhu X, Lu HY, Deng Q.
Disease models & mechanisms. 2017; 10(11):1323-1332.

Chemokine Signaling and the Regulation of Bidirectional Leukocyte Migration in Interstitial Tissues.
Powell D, Tauzin S, Hind LE, Deng Q, Beebe DJ, Huttenlocher A.
Cell reports. 2017; 19(8):1572-1585.

 

2016:

Rac2 Functions in Both Neutrophils and Macrophages To Mediate Motility and Host Defense in Larval Zebrafish.
Rosowski EE, Deng Q, Keller NP, Huttenlocher A.
Journal of immunology (Baltimore, Md. : 1950). 2016; 197(12):4780-4790.

EsxA membrane-permeabilizing activity plays a key role in mycobacterial cytosolic translocation and virulence: effects of single-residue mutations at glutamine 5.
Zhang Q, Wang D, Jiang G, Liu W, Deng Q, Li X, Qian W, Ouellet H, Sun J.
Scientific reports. 2016; 6:32618.

MicroRNAs in neutrophils: potential next generation therapeutics for inflammatory ailments.
Gurol T, Zhou W, Deng Q.
Immunological reviews. 2016; 273(1):29-47.

 

2015:

Adenosine signaling promotes hematopoietic stem and progenitor cell emergence.
Jing L, Tamplin OJ, Chen MJ, Deng Q, Patterson S, Kim PG, Durand EM, McNeil A, Green JM, Matsuura S, Ablain J, Brandt MK, Schlaeger TM, Huttenlocher A, Daley GQ, Ravid K, Zon LI.
The Journal of experimental medicine. 2015; 212(5):649-63.

 

2014:

Distinct innate immune phagocyte responses to Aspergillus fumigatus conidia and hyphae in zebrafish larvae.
Knox BP, Deng Q, Rood M, Eickhoff JC, Keller NP, Huttenlocher A.
Eukaryotic cell. 2014; 13(10):1266-77.

 

2013:

Localized bacterial infection induces systemic activation of neutrophils through Cxcr2 signaling in zebrafish.
Deng Q, Sarris M, Bennin DA, Green JM, Herbomel P, Huttenlocher A.
Journal of leukocyte biology. 2013; 93(5):761-9.

Low-volume toolbox for the discovery of immunosuppressive fungal secondary metabolites.
Berthier E, Lim FY, Deng Q, Guo CJ, Kontoyiannis DP, Wang CC, Rindy J, Beebe DJ, Huttenlocher A, Keller NP.
PLoS pathogens. 2013; 9(4):e1003289.

 

2012:

Leukocyte migration from a fish eye's view.
Deng Q, Huttenlocher A.
Journal of cell science. 2012; 125(Pt 17):3949-56.

Distinct signalling mechanisms mediate neutrophil attraction to bacterial infection and tissue injury.
Deng Q, Harvie EA, Huttenlocher A.
Cellular microbiology. 2012; 14(4):517-28.

 

2011:

Lyn is a redox sensor that mediates leukocyte wound attraction in vivo.
Yoo SK, Starnes TW, Deng Q, Huttenlocher A.
Nature. 2011; 480(7375):109-12<

Dual roles for Rac2 in neutrophil motility and active retention in zebrafish hematopoietic tissue.
Deng Q, Yoo SK, Cavnar PJ, Green JM, Huttenlocher A.
Developmental cell. 2011; 21(4):735-45.

 

2010:

Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish.
Yoo SK, Deng Q, Cavnar PJ, Wu YI, Hahn KM, Huttenlocher A.
Developmental cell. 2010; 18(2):226-36.

 

2008:

Modulation of host cell endocytosis by the type III cytotoxin, Pseudomonas ExoS.
Deng Q, Barbieri JT.
Traffic (Copenhagen, Denmark). 2008; 9(11):1948-57.

Molecular mechanisms of the cytotoxicity of ADP-ribosylating toxins.
Deng Q, Barbieri JT.
Annual review of microbiology. 2008; 62:271-88.

 

2007:

Intracellular trafficking of Pseudomonas ExoS, a type III cytotoxin.
Deng Q, Zhang Y, Barbieri JT.
Traffic (Copenhagen, Denmark). 2007; 8(10):1331-45.

Plasma membrane localization affects the RhoGAP specificity of Pseudomonas ExoS.
Zhang Y, Deng Q, Porath JA, Williams CL, Pederson-Gulrud KJ, Barbieri JT.
Cellular microbiology. 2007; 9(9):2192-201.

Intracellular localization of type III-delivered Pseudomonas ExoS with endosome vesicles.
Zhang Y, Deng Q, Barbieri JT.
The Journal of biological chemistry. 2007; 282(17):13022-32.

Pseudomonas aeruginosa ExoS ADP-ribosyltransferase inhibits ERM phosphorylation.
Maresso AW, Deng Q, Pereckas MS, Wakim BT, Barbieri JT.
Cellular microbiology. 2007; 9(1):97-105.

 

2005:

Uncoupling Crk signal transduction by Pseudomonas exoenzyme T.
Deng Q, Sun J, Barbieri JT.
The Journal of biological chemistry. 2005; 280(43):35953-60.

 

2003:

Isolation, expression pattern of a novel human RAB gene RAB41 and characterization of its intronless homolog RAB41P.
Guo JH, Chen L, Chen S, Liu X, Saiyin H, Deng Q, Zhuang Y, Wan B, Yu L, Zhao SY.
DNA sequence : the journal of DNA sequencing and mapping. 2003; 14(6):431-5.