Orellana, E.A., Rangasamy, L., Srinivasarao, M., Abdelaal, A.M., Low, P.S., Kasinski, A.L. (2018) Enhancing microRNA activity through increased endosomal release mediated by nigericin Currently available at bioRxiv. July 2018

Rangasamy, L., Chelvam, V., Kanduluru, A.K., Srinivasarao, M., Bandara, A.N., You, F., Orellana, E., Kasinski, A.L., Low, P.S. (2018) New mechanism for release of endosomal contents: osmotic lysis via nigericin-mediated K+/H+ exchange.  Bioconjugate Chemistry 2018 Feb 15

Zhou, W., Pal, A.S., Yi-Hui Hsu, A., Gurol, T., Zhu, Z., Wirbisky-Hershberger, S.E., Freeman, J., Kasinski, A.L., Deng, Q. (2017) MicroRNA-223 suppresses the canonical NF-kB pathway in basal keratinocytes to dampen neutrophilic inflammation. Cell Reports 2018 Feb 13;22(7):1810-1823


Orellana, E.A., and Kasinski A.L. (2017) No vehicle, no problem.  Oncotarget.

Pal, A.S., and Kasinski, A.L. (2017) Animal modles to study microRNA function. Advances in Cancer Research. Vol 135 pp53-118

Orellana, E.A., Tenneti, S., Rangasamy, R., Low, P.S., Kasinski, A.L. (2017) FolamiRs: Ligand-targeted, vehicle-free delivery of microRNAs for the treatment of cancer. Science Translational Medicine. August 2, 2017


Orellana, E.A., and Kasinski, A.L. (2016) Sulforhodamine B (SRB) assay in cell culture to investigate cell proliferation. Bio-Protocols. September 2016 


Orellana E.A., and Kasinski, A.L. (2015) MicroRNAs in cancer: A historical perspective on the path from discovery to therapy. Cancers 7(3), 1388-1405

Humphrey, S. and Kasinski, A.L. (2015) RNA guided CRISPR-Cas Technologies for Genome Scale Investigation of Disease Processes. Journal of Hematology and Oncology. 2015, 8 :31 (2 April 2015)


Kasinski, A.L., Kelner, K., Stahlhut, C., Orellana, E., Zhao, J., Shimer, E., Dysart, S., Chen, X., Bader, A.G., Slack, F.J. (2014) A combinatorial microRNA therapeutics approach to suppressing non-small cell lung cancer. Oncogene, September 2014

Kasinski, A.L., Boss, J., Khuri, F.R., Fu, H. (2014) Transcriptional regulation of YWHAZ, the gene encoding 14-3-3 zeta. PLoS-ONE, April, 2014


*Kasinski, A.L., *Slack, F.J. (2013) Small RNAs deliver a blow to ovarian cancer. * co-corresponding authors. Cancer Discovery, November 2013 3;1220

*Kasinski, A.L., Slack, F.J. (2013) Generation of mouse lung epithelial cells. Bio-Protocols. * corresponding author Bio Protocol article

Puckett, M.C., Goldman, E.H., Cockrell, L.M., Huang, B., Kasinki, A.L., Du, Y., Wang, C., Lin, A., Ichijo, H., Khuri, F.R., and Fu, H. (2013) Integration of the Apoptosis signal-regulating kinase 1-mediated stress signaling with the Akt/PKB-IkB kinase cascade. Mol Cell Biol 2013 Jun;33(11):2252-9


Kasinski, A.L., Slack, F.J. (2012) miRNA-34 prevents cancer initiation and progression in a therapeutically resistant Kras and p53-induced mouse model of lung adenocarcinoma. Cancer Research, Sept; 72, 5576-5587

Kasinski, A.L., Slack, F.J. (2012) Arresting the culprit: targeted antagomir delivery to sequester oncogenic miR-221 in HCC. Molecular Therapy – Nucleic Acids, March; 1(3):12


Kasinski, A.L., Slack, F.J. (2011) Therapeutic microRNAs en route to the clinic: progress in validating and targeting miRNAs for cancer therapy. Nature Reviews Cancer, Nov 24; 11(12):849-64

Kim, M., Kasinski, A.L., Slack, F.J. (2011) MicroRNA therapeutics in pre-clinical cancer models. Lancet Oncology, Apr;12(4):319-321

Kasinski, A.L., Fu, H. (2011) 14-3-3 zeta.  UCSD-Nature Molecule Pages. (doi:10.1038/mp.a000060.01)


Kasinski, A.L., Slack, F.J. (2010) Potential microRNA therapies targeting Ras, NFkB and p53 signaling.  Current Opinion in Molecular Therapeutics, Apr; 12(2):147-57

Earlier studies

Kasinski, A.L., Du, Y., Thomas, S., Zhao, J., Sun, S.Y., Khuri, F.R., Wang, C.Y., Shoji, M., Sun, A., Snyder, J., Liotta, D., Fu, H. (2008) Inhibition of IKK-NFkB signaling pathway by EF24, a novel monoketone analogue of curcumin.  Molecular Pharmacology Sep; 74(3):654-61

Park, H.R., Cockrell, L.M., Du, Y., Kasinski, A., Havel, J., Zhao, J., Reyes-Turcu, F., Wilkinson, K., Fu, H. (2008) Methods for Protein-Protein Interactions, Molecular Biomethods Handbook 2nd Edition.

Kasinski, A., Doering, C.B. and Danner, D.J. (2004) Leucine toxicity in a neuronal cell model with inhibited branched chain amino acid catabolism. Molecular Brain Research 122: 180-7.

Danner, D.J., Muller, E.A., Kasinski, A. (2004) The complexity of single gene disorders: Lessons from maple syrup urine disease and thiamin responsiveness.  Thiamine:  catalytic mechanisms and role in normal and disease states.  Ed by M.S. Patel and F. Jordan, Academic Press.

Nellis, M.M., Kasinski, A., Carlson, M., Allen, R., Schaefer, A.M., Schwartz, E.M., Danner, D.J. (2003) Relationship of causative genetic mutations in maple syrup urin disease with their clinical expression.  Mol. Genet. Metab. 80: 189-95

Nellis, M.M., Doering, C.B., Kasinski, A. and Danner, D.J. (2002) Insulin increases branched chain alpha-ketoacid dehydrogenase kinase expression in Clone 9 rat cells. Am J. Physiol. 238: E853-E860.