We are currently looking for post-doc positions! Please see the information below: 

Postdoc position in cryo-EM

An NIH-funded postdoc position is available in the lab of Dr. Leifu Chang in the Department of Biological Sciences of Purdue University.

The lab combines cryo-EM and biochemical reconstitution to understand the molecular mechanisms of large protein complexes, particularly those in cell cycle regulation and CRISPR-Cas systems. Refer to our recent publications for more details:


Dr. Chang’s lab has access to two Titan Krios electron microscopes, both equipped with K3 direct electron detectors, and a Talos F200C with a K2 detector. All microscopes are located in the same building as the Chang lab. The lab is also equipped with all the equipment necessary for standard molecular biology practices and protein expression and purification.

Candidates should have a Ph.D. (or equivalent) in biology, chemistry, physics, or computer science. Experience in protein expression and purification using insect cells and/or mammalian cells will be an advantage. Experience in cryo-EM and image processing is desired but not essential.

To apply, please contact Dr. Leifu Chang via email (lchang18@purdue.edu).

Graduate Student and Undergraduate Opportunities

Dr. Chang is currently accepting rotation students from both the Department of Biological Sciences and the PULse Program graduate programs here at Purdue University! Thanks to everyone interested in our lab, and we hope you all enjoy your time with us! As well, new undergraduate research positions are available to students wanting to start to learn about structural biology research!

If you would like to collaborate or inquire about opportunities within our lab, please contact us via the emails provided on the People page.