51. Liu Y, Zhu W, Tan Y, Nakayasu ES, Staiger CJ, Luo ZQ. 2017. A Legionella effector disrupts host cytoskeletal structure by cleaving actin. PLoS Pathog. 2017;13(1):e1006186.PMID: 28129393

50.  Qiu J, Sheedlo MJ, Yu K, Tan Y, Nakayasu ES, Das C, Liu X, Luo ZQ. 2016. Ubiquitination independent of E1 and E2 enzymes by bacterial effectors. Nature. 533:120-124. PMID: 27049943 (Highlighted and commented by Nature, Molecular Cell, Current Biology, Nature Review Microbiology and Science Signaling).

49. Lu C, Nakayasu ES, Zhang LQ*, Luo ZQ*. Identification of Fic-1 as an enzyme that inhibits bacterial DNA replication by AMPylating GyrB, promoting filament formation. Sci Signal. 2016 Jan 26;9(412):ra11. doi: 10.1126/scisignal.aad0446. PMID: 26814232

48. Sheedlo MJ, Qiu J, Tan Y, Paul LN, Luo ZQ*, Das C*. Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination. Proc. Natl. Acad. Sci. USA. 2015 Dec 8;112(49):15090-5. doi: 10.1073/pnas.1514568112. Epub 2015 Nov 23. PMID: 26598703

47. Zhu W, Luo Z.-Q. 2015 Cell biology and immunology lessons taught by Legionella pneumophila. Sci China Life Sci. 2015 Nov 23. PMID: 26596966

46. Wang T, Si M, Song Y, Zhu W, Gao F, Wang Y, Zhang L, Zhang W, Wei G, Luo ZQ, Shen X. 2015. Type VI Secretion System Transports Zn2+ to Combat Multiple Stresses and Host Immunity.  PLoS Pathog.  Jul 2;11(7):e1005020. doi: 10.1371/journal.ppat.1005020. eCollection 2015 Jul.PMID:26134274

45. Luo X, Wasilko DJ, Liu Y, Sun J, Wu X, Luo ZQ, Mao Y. 2015. Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome. PLoS Pathog. Jun 12;11(6):e1004965. doi: 10.1371/journal.ppat.1004965. eCollection 2015 Jun. PMID: 26067986

44. Zhu W, Luo ZQ. 2015. A new way to detect the danger: Lysosomal cell death induced by a bacterial ribosomal protein. J Nat Sci.  Jun;1(6). pii: e107. PMID: 26052550

43. Zhu W., Tao L., Quick M.L,. Joyce J.A., Qu J.M., Luo Z.-Q. 2015. Sensing cytosolic RpsL by macrophages induces lysosomal cell death and termination of bacterial infection. PLoS Pathogens. 11(3):e1004704. doi: 10.1371/journal.ppat.1004704. eCollection 2015 Mar. †,equal contribution authors. PMID:25738962

42. Hsu F., Luo X., Qiu J., Teng Y.B., Jin J., Smolka M.B., Luo Z.-Q*., Mao Y*. 2014. The Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling. Proc. Natl. Acad. Sci. USA. 111(29):10538-43. doi: 10.1073/pnas.1402605111. Epub 2014 Jul 8. †,equal contribution authors. PMID:25006264

41. Cui B., Wang Y., Song Y., Wang T., Li C., Wei Y., Luo Z.-Q.*, Shen X*. 2014. Bioluminescence resonance energy transfer system for measuring dynamic protein-protein interactions in bacteria. mBio. 20;5(3):e01050-14. PMID: 24846380

40. Guo Z., Stephenson R., Qiu J., Zheng S., Luo Z.-Q. 2014. A Legionella effector modulates host cytoskeletoal structure by inhibiting actin polymerization. Microbes and Infection 2014;16(3):225-36 PMID: 24286927

39. Qiu J. and Luo, Z.-Q. 2013. Effector translocation by the Legionella Dot/Icm type IV secretion system.  Curr Top Microbiol Immunol. 376:103-15 PMID: 23918176

38. Weber M.M., Chen C., Rowin K., Mertens K., Galvan G., Zhi H., Dealing C.M., Roman V.A., Banga S., Tan Y., Luo Z.-Q, Samuel J.E. 2013. Identification of C. burnetii type IV secretion substrates required for intracellular replication and Coxiella-containing vacuole formation. J Bacteriol. 195(17):3914-24. PMID: 23813730

37. Ma J., He Y., Hu B., Luo Z.-Q. 2013. Genome Sequence of an Environmental Isolate of the Bacterial Pathogen Legionella pneumophilaGenome Announc. 2013. Jun 27;1(3). doi:pii: e00320-13.PMID: 23792742

36. Zhu W., Hammad L.A., Hsu .F., Mao Y., Luo Z.-Q.  2013. Induction of caspase 3 activation by multiple Legionella pneumophila Dot/Icm substrates. Cell Microbiol.  2013. 15(11):1783-95. PMID: 23773455

35. Tao L., Zhu W., Hu B.J., Qu J.M., Luo Z.-Q. 2013 Induction of rapid cell death by an environmental isolate of Legionella pneumophila in mouse macrophages. Infect Immun. 2013 81(9):3077-88. †,equal contribution authors. PMID:23753633

34. Sun E.W., Wagner M.L., Maize A., Kemler D., Garland-Kuntz E., Xu L., Luo Z.-Q, Hollenbeck P.J.  Legionella pneumophila infection of Drosophila S2 cells induces only minor changes in mitochondrial dynamics. PLoS One. 2013, 30;8(4):e62972.

33. Xu L. and Luo Z.-Q. 2013 Cell Biology of infection by Legionella pneumophila. Microbes and Infection. 2013, 15(2):157-67. PMID:23159466

32. Zhu W. and Luo Z.-Q. 2012  Methods for Determining Protein Translocation by the Legionella pneumophila Dot/Icm Type IV Secretion System. Methods Mol Biol. 954:323-32. PMID:23150405

31. Hsu F., Zhu W., Brennan L., Tao L, Luo ZQ, Mao Y. 2012. Structural basis for substrate recognition by a unique Legionella phosphoinositide phosphatase. Proc. Natl. Acad. Sci. USA.  109:13567-72. PMID:23150405

30. Luo Z.-Q. 2012. Legionella secreted effectors and innate immune responses. Cellular Microbiology. 14:19-27. PMID: 21985602

29. Tan Y. Arnold A. J. and Luo Z.-Q. 2011. Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination. Proc. Natl. Acad. Sci. USA. 108:21212-7 PMID: 22158903

28. Tan Y. and Luo Z.-Q. 2011. Take it and release it: the use of the Rab1 small GTPase at a bacterium's will. Cellular Logistics. 1:4, 1-3.

27. Jain, P., Luo, Z.-Q., & Blanke, S. R. 2011. Helicobacter pylori VacA engages the mitochondrial apoptotic machinery by inducing Drp1-mediated mitochondrial fission. Proc. Natl. Acad. Sci. USA. 108:16032-7. PMID: 21903925

26. Tan Y. and Luo Z.-Q. 2011. Legionella pneumophila SidD is a deAMPylase that modifies Rab1. Nature. 475:506-509. PMID: 21734656. (Highlighted and commented by Cell Host & Microbe and cited by Faculty 1000 as a "Must Read" ariticle).

25. Zhu W., Banga S., Tan Y., Zheng C., Stephenson R., Gately J. and Luo Z.-Q. 2011. Comprehensive identification of protein substrates of the Dot/Icm type IV transporter of Legionella pneumophila.  PLoS One .6(3):e17638. PMID: 21408005

24. Huang L, Boyd, D, Amyot W.M., Hempstead A.D., Luo Z.-Q., O'Connor T.J., Chen C., Machner, M., Montminy T., Isberg R.R. 2011. The E block motif is associated with Legionella pneumophila translocated substrates Cell Microbiol. 13:227-45. PMID:21687427

23. Luo Z.-Q. Striking a balance: Modulation of host cell death pathways by Legionella pneumophila. 2011. Front. Microbio. doi: 10.3389/fmicb.2011.00036 PMID: 21687427.

22. Luo Z.-Q. 2011.Targeting one of its own: expanding roles of substrates of the Legionella pneumophila Dot/Icm type IV secretion system. 2011. Front. Microbio. 2:31. doi: 10.3389/fmicb.00031 PMID: 21687422.

21. Fontana M. F., Banga S., Barry K. C., Shen X., Tan, Y., Luo Z.-Q*. and Vance E.V*.  2011. Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila.  PLoS Pathogens. 7: e1001289. PMID: 21390206 

20. Chen C†. Banga, S†., Mertens, K†., Weber M., Gorbaslieva, I.,Tan Y., Luo, Z.-Q*. and Samuel J. E. * 2010 Large-scale identification and translocation of Type IV secretion substrates by Coxiella burnetii Proc Natl Acad Sci USA. 107:21755-21760. †, equal contribution authors *,corresponding authors. PMID: 21098666. 

19.Mei G.Y., Yan X.X. Turak A. Luo Z.-Q. and Zhang L. Q. 2010.  AidH, an alpha/beta-hydrolase fold family member from an Ochrobactrum sp. strain, is a novel N-acylhomoserine lactonaseAppl Environ Microbiol. 76:4933-42. PMID: 20525860

18. Xu L., Shen X., Bryan A., Banga S., Swanson M. and Luo ZQ. 2010. Inhibition of host vacuolar H+-ATPase activity by a Legionella pneumophila effector PLoS Pathogens 19;6(3):e1000822. †, equal contribution authors, PMID: 20333253

17. Shen X., Banga S., Liu Y., Xu L., Gao P., Shamovsky I., Nudler E. and Luo Z.-Q. 2009. Targeting eEF1A by a Legionella pneumophila effector leads to inhibition of protein synthesis and induction of host stress response. Cellular Microbiology. 11: 911-926. PMID: 19386084

16. Liu Y., Gao P. Banga S. and Luo Z.-Q.  2008. An in vivo gene deletion system for determining temporal requirement of bacterial virulence factors. Proc. Natl. Acad. Sci. USA. 105:9385-90. (cited by Faculty 1000). PMID: 18599442

15. Banga, S., Gao, P., Shen X., Fiscus V., Zong W-X., Chen L. and Luo Z.-Q. 2007. Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family. Proc. Natl. Acad. Sci. USA. 104: 5121-5126. PMID: 17360363

14. Liu, Y. and Luo Z.-Q. 2007. The Legionella pneumophila effector SidJ Is required for efficient recruitment of endoplasmic reticulum proteins to the bacterial phagosome. Infection and Immunity 75:592-603. PMID: 17101649

13. Conover G., Martinez-Morales F., Heidtman M., Luo Z.-Q.,Tang M., Chen C., Geiger O., and Isberg R. R. 2008 Phosphatidylcholine synthesis is required for optimal function of Legionella pneumophila virulence determinants.  Cell Microbiology 10:514-28. PMID: 17979985

12. VanRheenen, S. M. Luo Z.-Q., O’Connor, T. and Isberg R. R.  2006. Members of a Legionella pneumophila family of proteins with ExoU/phospholipase A active sites are translocated to target cells. Infection and Immunity. 74: 3597-606. PMID: 16714592

11. Luo, Z.-Q. and Isberg R. R. 2004. Multiple substrates of the Legionella pneumophila Dot/Icm system identified by interbacterial protein transfer. Proc. Natl. Acad. Sci. USA. 101:  841-846. (cited by Faculty 1000). PMID: 14715899

10. Qin, Y, Luo Z.-Q, Farrand S. K. 2004. Domains formed within the N-terminal region of the quorum- sensing activator TraR are required for transcriptional activation and direct interaction with RpoA from Agrobacterium. Journal of Biological Chemistry.  279:40844-51

9. Luo, Z.-Q., Su S. and Farrand S. K.  2003.  In situ activation of the quorum-sensing transcription factor TraR by cognate and non-cognate acyl-Homoserine lactone ligands: kinetics and consequences. Journal of Bacteriology 185: 5665-5672.

8. Luo Z.-Q, Smyth AJ. Gao P, Qin Y, Farrand S. K. 2003. Mutational analysis of TraR: Correlating function with molecular structure of a quorum-sensing transcriptional activator. Journal of Biological Chemistry 278:13173-82.

7. Luo Z.-Q. and Farrand S. K. 2001.  The Agrobacterium tumefaciens rnd homolog is required for TraR-mediated quorum-dependent activation of Ti plasmid tra gene expression. Journal of Bacteriology 183:3919-3930.

6. Luo Z.-Q., Clemente T., and Farrand S. K. 2001. Construction of a derivative of Agrobacterium tumefaciens C58 that does not mutate to tetracycline resistance.  Molecular Plant-Microbe Interaction 14:98-103.

5. Qin Y., Luo Z.-Q., Smyth A. J., Gao P., Beck Von Bodman S., Farrand S. K. 2000. Quorum-sensing signal binding results in dimerization of TraR and its release from membranes into the cytoplasm.  The EMBO Journal 19:5212-5221.

4. Luo Z.-Q., Qin Y., and Farrand S. K. 2000. The antiactivator TraM interferes with the autoinducer-dependent binding of TraR to DNA by interacting with the C-terminal region of the quorum-sensing activator.  Journal of Biological Chemistry 275:7713-7722.

3. Luo, Z.-Q. and Farrand, S. K. 1999. Signal-Dependent DNA binding and functional domains of the quorum-sensing activator TraR as identified by repressor activity.  Proc. Natl. Acad. Sci. USA.  96: 9009-9014.

2. Luo, Z.-Q. and Farrand, S. K. 1999.  Cloning and characterization of a tetracycline resistance determinant present in Argobacterium tumefaciens C58.  Journal of Bacteriology 181: 618-626.

1. Hwang I., Smyth A., Luo Z.-Q., and Farrand S. K.  1999.  Modulating quorum-sensing: The antiactivatorTraM inhibits TraR-activation of Ti plasmid conjugal transfer by protein-protein interaction.  Molecular Microbiology 34: 282-294.