Picture of KIM

CHANG H. KIM

Department of Comparative Pathobiology
Section Head of Microbiology & Immunology
Professor of Immunology
Graduate Studies Committee Chair
Courtesy Appointment
VPTH 126
Phone: 765-494-0976

Cell trafficking and function in the hematolymphoid system

We study trafficking mechanisms of lymphocytes for development and effector functions. Special emphasis is on the roles of chemokine receptors and integrins in regulation of the trafficking of various T cell populations (Th17, Th1, Tfh, Tfr, IL-10+ T cells, and FoxP3+ Tregs) and innate lymphoid cells (ILCs).

Mucosal immunity, inflammation, and cancer

Balanced immunity is important for prevention of inflammation and cancer. We study the interactive relationships among immunity, inflammation and cancer development in the intestine. The cooperative roles of T cells, B cells, dendritic cells and innate lymphoid cells are studied.

Host and microbial metabolites in regulation of the immune system

Metabolites produced from dietary factors play important roles in regulation of immunity and inflammation. We study the roles of short-chain fatty acids (SCFAs) and retinoic acid. Short-chain fatty acids are produced by gut commensal bacteria from fermentation of dietary fibers. Retinoic acid is produced from vitamin A. These two different types of metabolites promote immunity and prevent inflammatory responses in the body. In addition, we study the functions of sex hormones and related factors in regulation of immunity and inflammatory processes.

Chang H. Kim, Ph.D.
Professor of Immunology and Section Head
Microbiology, Immunology and Molecular Genetics
Department of Comparative Pathobiology, Purdue Veterinary Medicine
http://www.vet.purdue.edu/discovery/kim/index.php

Program Leader, Inflammation and Immunology,
Purdue Institute of Inflammation, Immunology, Infectious Diseases
http://www.purdue.edu/discoverypark/pillars/pi4d/index.php

Weldon School of Biomedical Engineering
https://engineering.purdue.edu/BME/People/ptProfile?resource_id=90137

Center for Cancer Research, Purdue University
http://www.cancerresearch.purdue.edu/

Professional Faculty Research

Cell trafficking and function in the hematolymphoid system
Mucosal immunity, inflammation, and cancer
Host and microbial metabolites in regulation of the immune system

Purdue University Biological Sciences, 915 W. State Street, West Lafayette, IN 47907

Main Office: (765) 494-4408   Business Office: (765) 494-4764  Contact Us

© 2015 Purdue University | An equal access/equal opportunity university | Copyright Complaints

Trouble with this page? Disability-related accessibility issue? Please contact the College of Science Webmaster.

Maintained by Science IT