David Sanders Lab


Michael T. Osterholm, Kristine A. Moore, Nicholas S. Kelley, Lisa M. Brosseau, Gary Wong, Frederick A. Murphy, Clarence J. Peters, James W. LeDuc, Phillip K. Russell, Michel Van Herp, Jimmy Kapetshi, Jean-Jacques T. Muyembe, Benoit Kebela Ilunga, James E. Strong, Allen Grolla, Anja Wolz, Brima Kargbo, David K. Kargbo, Pierre Formenty,   David Avram Sanders, Gary P. Kobinger; Transmission of Ebola Viruses: What We Know and What We Do Not Know; doi: 10.1128/mBio.00137-15 19 February 2015 mBio vol. 6 no. 2 e00137-15: PMC25698835

Soma Mukhopadhyay, Thomas Hansen, Peter Schönheit, Miriam S. Hasson and David Avram Sanders. (2013) Atomic Structure of a Hyperthermophilic Acetate Kinase. Acetate: Versatile Building Block of Biology and Chemistry. Chapter 2: 15-28. Nova Science Pub. Inc.

Selvarajah S, Sexton NR, Kahle KM, Fong RH, Mattia K-A, Gardner J., Lu K., Liss N.M., Salvador B., Tucker D. F., Barnes T., Mabila M., Zhou X., Rossini G., Rucker J. B., Sanders D. A., Suhrbier A., Sambri V., Michault A., Muench M. O., Doranz B. J., Simmons G.  (2013) A Neutralizing Monoclonal Antibody Targeting the Acid-Sensitive Region in Chikungunya Virus E2 Protects from Disease. PLoS Negl Trop Dis 7(9): e2423. doi:10.1371/journal.pntd.0002423: PMC24069479

Frossard, SM, Khan AA, Warrick EC, Gately JM, Hanson AD, Oldham ML, Sanders DA, Csonka LN (2012) Identification of a Third Osmoprotectant Transport System, OsmU in Salmonella enterica. J Bacteriol. 194, 3861-3871.

Apte, S., Sanders, DA. (2010) Effects of retroviral envelope-protein cleavage upon trafficking incorporation and membrane fusion. Virology 405, 214-224

Mukhopadhyay, S., Hasson, M.S., and Sanders, D.A. (2008) A continuous assay of acetate kinase activity: Measurement of inorganic phosphate release generated by hydroxylaminolysis of acetyl phosphate. Bioorg Chem 36, 65-69.

Brindley, M. A., L. Hughes, A. Ruiz, P. B. McCray, Jr., A. Sanchez, D. ASanders, and W. Maury (2007) Ebola virus glycoprotein 1: Identification of residues important for binding and postbinding events. J Virol 81, 7702-7709.

Alvarado, J., Ghosh, A., Janovitz, T., Jauregui, A., Hasson, M.S., and Sanders, D.A. (2006). Origin of Exopolyphosphatase Processivity: Fusion of an ASKHA Phosphotransferase and a Cyclic Nucleotide Phosphodiesterase Homolog. Structure. 14, 1263-1272.

Strang B. L., Takeuchi Y., Relander T., Richter J., Bailey R., Sanders D.A., Collins M.K., and Ikeda Y. (2005). Human immunodeficiency virus type 1 vectors with alphavirus envelope glycoproteins produced from stable packaging cells. J Virol. 79:1765-1771.

Sanders, D.A. and B. L. Wanner (2005). Polyphosphate: From Bugs to Brains. Encyclopedia of Life Sciences online.

Sanders, D. A. (2004). Ebola virus glycoproteins: guidance devices for targeting gene therapy vectors. Expert Opin Biol Ther 4, 329-336. Kahl, C. A., Marsh, J., Fyffe, J., Sanders, D. A., and Cornetta, K. (2004). Human immunodeficiency virus type 1-derived lentivirus vectors pseudotyped with envelope glycoproteins derived from Ross River virus and Semliki Forest virus. J Virol. 78, 1421-1430.

Taylor, G. M., Zullo, A. J., Larson, G. A. and Sanders, D. A. (2003). Promotion of retroviral entry in the absence of envelope protein by chlorpromazine. Virology316, 184-189.

Diao, J., Cooper, D. R., Sanders, D. A., Hasson, M. S. (2003) Crystallization of butyrate kinase 2 from Thermotoga maritima mediated by vapor diffusion of acetic acid. Acta Cryst. D 59, 1100-1102.

Taylor, G. M. and Sanders, D. A. (2003). Structural criteria for regulation of membrane fusion and virion incorporation by the MuLV TM cytoplasmic domain,Virology 312, 295-305.

Sinn, P. L., Hickey, M. A., Staber, P. D., Dylla, D. E., Jeffers, S. A., Davidson, B. L., Sanders, D. A., and McCray, P. B., Jr. (2003). Lentivirus vectors pseudotyped with filoviral envelope glycoproteins transduce airway epithelia from the apical surface independently of folate receptor alpha. J Virol. 77, 5902-5910.

Sanders, D. A. (2003). Ancient viruses in the fight against HIV. Drug Discovery Today 8, 287-291.

Jeffers, S. A., Sanders, D. A., and Sanchez, A. (2002). Covalent modifications of the Ebola virus glycoprotein. J Virol 76, 12463-12472. Sanders, D. A. (2002). No false start for novel pseudotyped vectors. Curr Opin Biotechnol 13, 437-442.

Kang, Y., Stein, C. S., Heth, J.A., Sinn, P. L., Penisten, A.K., Staber, P. D., Ratliff, K. L., Shen, H., Barker, C. K., Martins, I., Sharkey, C. M., Sanders, D. A., McCray, P. B., and Davidson, B. L. (2002). In vivo gene transfer using a nonprimate lentiviral vector pseudotyped with Ross River virus glycoproteins. J Virol. 76, 9378-9388.

Taylor, G. M., Gao, Y., and Sanders, D. A. (2001). Fv-4: identification of the defect in env and the mechanism of resistance to ecotropic murine leukemia virus. J Virol. 75, 11244-11248.

Sharkey, C. M., North, C. L., Kuhn, R. J., and Sanders, D. A., (2001). Ross River virus glycoprotein-pseudotyped retroviruses and stable cell lines for their production. J Virol. 75, 2653-2659.

Buss, K. A., Cooper, D. R., Ingram-Smith, C., Ferry, J.G., Sanders, D. A., and Hasson, M. S. (2001). Urkinase: Structure of acetate kinase, a member of the ASKHA superfamily of phosphotransferases. J Bacteriology 183, 680-686.

Blanton, J. R., Jr., Bidwell, C. A., Sanders, D. A., Sharkey, C. M., McFarland, D. C., Gerrard, D. E., and Grant, A. L. (2000). Plasmid transfection and retroviral transduction of porcine muscle cells for cell-mediated gene transfer. J Anim Sci 78, 909-918.

Sanders, D. A. 2000. Sulfhydryl involvement in fusion mechanisms, p. 483-514. In H. Hilderson and S. Fuller (ed.), Fusion of biological membranes & related problems. Kluwer Academic/Plenum Publishers, NY.

Taylor, G. M. and Sanders, D. A. (1999). The role of the membrane-spanning-domain sequence in glycoprotein-mediated membrane fusion. Molecular Biology of the Cell 10, 2803-2815.

Buss, K., Ingram-Smith, C., Ferry, J. G., Sanders, D. A., and Hasson, M. S. (1997). Crystallization of acetate kinase from Methanosarcina thermophila and prediction of its fold. Protein Science 6, 2659-2662.

Pinter, A., Kopelman, R., Li, Z., Kayman, S. C., and Sanders, D. A. (1997). Localization of the labile disulfide bond between SU and TM of the murine leukemia virus envelope protein complex to a highly conserved CWLC motif in SU that resembles the active site sequence of thiol-disulfide exchange enzymes. J Virol 71, 8073-8077.

Lodge, R., Delamarre, L., Lalonde, J.-P., Alvarado, J., Sanders, D. A., Dokh?lar, M.-C., Cohen, ?. A., and Lemay, G. (1997). Two distinct oncornaviruses harbor an intracytoplasmic tyrosine-based basolateral targeting signal in their viral envelope glycoprotein. J. Virol. 71, 5696-5702.

Sanders, D. A., Gillece-Castro, B. L., Burlingame, A. L., and Koshland, D. E., Jr. (1992). Phosphorylation site of NtrC, a protein phosphatase whose covalent intermediate activates transcription. J Bacteriol 174, 5117-5122.

Bourne, H. R., Sanders, D. A., and McCormick, F. (1991). The GTPase superfamily: conserved structure and molecular mechanism. Nature 349, 117-127.

Bourne, H. R., Sanders, D. A., and McCormick, F. (1990). The GTPase superfamily: a conserved switch for diverse cell functions. Nature 348, 125-132.

Sanders, D. A. (1990). A guide to low molecular weight GTPases. Cell Growth Differ 1, 251-258.

Sanders, D. A., Gillece-Castro, B. L., Stock, A. M., Burlingame, A. L., and Koshland, D. E., Jr. (1989). Identification of the site of phosphorylation of the chemotaxis response regulator protein, CheY. J Biol Chem 264, 21770-21778.

Sanders, D. A., Mendez, B., and Koshland, D. E., Jr. (1989). Role of the CheW protein in bacterial chemotaxis: overexpression is equivalent to absence. J Bacteriol171, 6271-6278.

Sanders, D. A., and Koshland, D. E., Jr. (1988). Receptor interactions through phosphorylation and methylation pathways in bacterial chemotaxis. Proc Natl Acad Sci U S A 85, 8425-8429.