Genomics Horvath S. DNA methylation age of human tissues and cell types. Genome Biol. 2013 Oct 21;14(10):R115. [Epub ahead of print] PubMed PMID: 24138928. News coverage: Scientists Discover New Biological Clock With Age-Measuring Potential News: FDA Tells Google-Backed 23andMe to Halt DNA Test Service Evolution Kolb AW, Ané C, Brandt CR. Using HSV-1 Genome Phylogenetics to Track Past Human […]
Saturday, October 12, 2013
Genetics/Genomics Mali P, Esvelt KM, Church GM. Cas9 as a versatile tool for engineering biology. Nat Methods. 2013 Sep 27;10(10):957-63. doi: 10.1038/nmeth.2649. PubMed PMID: 24076990. Esvelt KM, Mali P, Braff JL, Moosburner M, Yaung SJ, Church GM. Orthogonal Cas9 proteins for RNA-guided gene regulation and editing. Nat Methods. 2013 Sep 29. doi: 10.1038/nmeth.2681. [Epub ahead of print] PubMed […]
Filed in journal watch
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Also tagged Alzheimer's Disease, behaviour, complex disease, CRISPR, CRISPR-CAS, disease, genetics, Genome editing, genomics, medicine, vision, visual motor response, VMR
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Tuesday, September 3, 2013
Genetics Xiao A, Wang Z, Hu Y, Wu Y, Luo Z, Yang Z, Zu Y, Li W, Huang P, Tong X, Zhu Z, Lin S, Zhang B. Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. Nucleic Acids Res. 2013 Aug 1;41(14):e141.doi: 10.1093/nar/gkt464. Epub 2013 Jun 6. PubMed PMID: 23748566; PubMed Central PMCID: PMC3737551. Wei C, Liu […]
Stem cells Hou P, Li Y, Zhang X, Liu C, Guan J, Li H, Zhao T, Ye J, Yang W, Liu K, Ge J, Xu J, Zhang Q, Zhao Y, Deng H. Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science. 2013 Aug 9;341(6146):651-4. doi: 10.1126/science.1239278. Epub 2013 Jul 18. PubMed PMID: […]
Filed in journal club
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Also tagged brain, cone photoreceptors, CRISPR, CRISPR-CAS, induced pluripotent stem cells, iPSCs, memory, mitochondrial eve, neuroscience, olfaction, regeneration, retina, small molecules, stem cells, vision, Y-chromosomal adam
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Robert Carmer, an HHMI Summer Undergrate Student, was featured in the press releases of the College of Science and Department of Biological Sciences. Also see him describing his research experience in this video.
Sylvia and Fai attended the 2013 Annual Meeting of the Association for Research in Vision and Ophthalmology and presented their work on novel signal transduction for photoreceptor development and using traditional Chinese medicine to treat retinal degeneration. Sylvia received a National Eye Institute Travel Grant and Yeunkyung Woo Achieve Excellence Travel Award to attend the […]
Filed in Fai's sharing, lab activities, pictures
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Also tagged ARVO, ARVO 2013, Association for Research in Vision and Ophthalmology, leung lab, purdue, retinal development, sylvia bonilla, TCM, Traditional Chinese Medicine, yuk fai leung
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Nature Special Issue on “The Future of Publishing“ Neuroscience Horikawa T, Tamaki M, Miyawaki Y, Kamitani Y. Neural Decoding of Visual Imagery During Sleep. Science. 2013 Apr 4. [Epub ahead of print] PubMed PMID: 23558170. Chung K, Wallace J, Kim SY, Kalyanasundaram S, Andalman AS, Davidson TJ, Mirzabekov JJ, Zalocusky KA, Mattis J, Denisin AK, […]
I visited Ho Yu College in Hong Kong last month. A good mentor Dr. William Mak has been running a great biotechnology education program for the primary and secondary school students, as well as the public there. See an old post about their outreach program in which they fit a whole research lab into custom-built […]
Sunday, February 10, 2013
Gene Therapy/Retinal degeneration Cideciyan AV, Jacobson SG, Beltran WA, Sumaroka A, Swider M, Iwabe S, Roman AJ, Olivares MB, Schwartz SB, Komáromy AM, Hauswirth WW, Aguirre GD. Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvement. Proc Natl Acad Sci U S A. 2013 Jan 22. [Epub ahead […]
Thursday, November 22, 2012
On 12th November 2012, Prof. Calvin Chi-Pui Pang from the Chinese University of Hong Kong and Prof. Haoyu Chen from the Joint Shantou International Eye Center (JSIEC), Shantou University & the Chinese University of Hong Kong visited the Leung Lab and the research facilities at Purdue University. Prof Pang and Chen first met with Prof. […]