Posts tagged ‘leung lab’

At Purdue, five zebrafish laboratories (Qing Deng, Daniel Suter, Yuk Fai Leung, David Umulis, Guangjun Zhang) have a joint lab meeting called FLAME (zebraFish LAb MEeting). We not only meet regularly to discuss science, but we also have fun together. On 5/13/2019, we concluded another productive year by hiking together at the Turkey Run State Park.

The FLAME group

The Flame Group

Fai leading the younger generation.

 

Logan climbing up the (academic) ladder.

Fai and Isaac!

 

Emre attended the Purdue Undergraduate Research Conference 2019 and presented a poster entitled “Investigating Inhibition of Apoptosis as a Novel Treatment for Retinitis Pigmentosa using a Transgenic Zebrafish Model”.

Emre presenting his work at the Purdue Undergraduate Research Conference.

 

Emre Coskun, Rebecca James, Logan Ganzen, Truc Kha and Yuk Fai Leung attended the 134th Annual Meeting for the Indiana Academy of Science in Indianapolis, IN on March 30th, 2019. All students presented at the meeting.

The Leung Lab!

Logan Ganzen, our graduate student, presented his work identifying a FDA-approved drug for treating night blindness.

Logan presenting his work.

Emre Coskun (right) presented his work on “Investigating Inhibition of Apoptosis as a Novel Treatment for Retinitis Pigmentosa using a Transgenic Zebrafish Model”.

 

Rebecca James presented her work on “Utilization of a Zebrafish Visual Motor Response Assay to Discover FDA Approved Drugs to Treat Retinitis Pigmentosa”

 

On 11/12/2018, Emre Coskun attended the Purdue Fall Undergraduate Research Exposition and presented a poster of his undergraduate reserarch work on “A Pharmacological Model of TRPA1-Mediated Nociception in the Zebrafish for Therapeutic Discovery”. This project was conceived by our graduate student Logan Ganzen. Logan and Emre worked closely to develop the foundation of this research project, and established zebrafish as a model for screening drugs to alleviate pain in patients.

Emre presenting his undergraduate research work.

 

On 11/10/2018, Logan Ganzen and Yuk Fai Leung attended the 2018 Sensorium at Purdue University. Logan gave a talk on “Drug Screening and Hit Identification for Retinitis Pigmentosa with Zebrafish” and shared our latest discoveries on using zebrafish to find new drugs to treat night blindness.

Logan described how we used zebrafish model of night blindness to screen and find new drugs to treat the disease.

Logan described the therapeutic effect of a positive compound that he identified in his doctoral research.

 

In May 2017, the Leung lab visited several collaborating groups in Asia and shared with them our research vision on using zebrafish to find new drugs for retinal degeneration. In this blog post, we will share some pictures of our visit to the the Eye Hospital at Wenzhou Medical University in China. We were hosted by Dr. Zibing Jin, a very accomplished vision scientist. We visited the University campus, and the eye hospital. Logan and Fai presented their work and interacted with the local students. Fai was also invited to be the external examiner of six master students and attended their oral defence. We also visit Yandang Mountains, a famous national geological park in China.

Wenzhou Medical University has a very pretty main campus in Chashan, with nice open space for the students.

Main campus of Wenzhou Medical University in Chashan

They have a whole building of 14 floors dedicated for different aspects of eye research!

Dr. Zibing Jin explaining the research programs in the Eye Hospital at Wenzhou Medical University.

Dr. Zibing Jin’s research group is accomplishing very well in recent years. They study genetics, stem cells, and animal models including zebrafish! In 2017 spring, they published three articles in the Proceedings of the National Academy of Sciences, one of the most influential journals in the world.

Dr Zibing Jin sharing his group’s research achievements to Logan and Fai

The Leung lab has been working with Dr. Jin’s group for years. During this trip, Fai outlined his research vision; whereas Logan presented his recent findings to the students.

Fai outlined his research vision to the students at Wenzhou Medical University.

Logan presented his latest findings to the students at Wenzhou Medical University.

Dr. Jin invited Fai to be an external examiner of six master students, whom had their oral defence during our visit. All these students had an extremely positive attitude and were very prolific! They all publish their work in international journals as first author, and contributed to many other lab projects as co-author.

Fai as external examiner of six master students’ oral defence at Wenzhou Medical University.

(Front row) Fai and four other external examiners. (Back row) Dr. Jin and six of his master students.

Enjoying local cuisine with colleagues.

Fai and Logan also visited Yandang Mountains, a famous national geological park in China, with several colleagues.

Logan, Fai and colleagues at Yandang mountains.

Logan and Fai at Yandang mountains. The  Chinese characters on the monument are literally “Yandang mountains”.

In May 2017, the Leung lab visited several collaborating groups in Asia and shared with them our research vision on using zebrafish to find new drugs for retinal degeneration. In this blog post, we will share some pictures of our visit to the Department of Ophthalmology and Visual Sciences (DOVS) at the Chinese University of Hong Kong in the next paragraph. We will also share some pictures of our attendance of the International Conference of Vision & Eye Research at the end of this post.

In DOVS, Dr. Wai Kit Chu from this department and Fai organized a “CUHK Ophthalmic Research Centre Joint Symposium” and invited local experts in ophthalmology and neuroscience to share our latest research findings with each other. Fai outlined our lab’s research program on discover new drugs for retinal degeneration by zebrafish research. Logan presented a talk entitled “Visual Motor Response of a Transgenic Retinitis Pigmentosa Zebrafish Model”.

The CUHK Ophthalmic Research Centre Joint Symposium.
From left to right, 1st row: Mr Jeremiah Palmerston, Dr Wai Kit Chu, Dr Yuk Fai Leung and Mr Logan Ganzen.
From left to right, 2nd row: Dr Rosa Chan, Dr Geoffrey Lau, Dr Wenjun Xiong and Dr Amy Lo.

Fai outlined our lab’s research program on discover new drugs for retinal degeneration by zebrafish research.

Logan presented a talk entitled “Visual Motor Response of a Transgenic Retinitis Pigmentosa Zebrafish Model”.

Dr. Amy Lo from the Department of Ophthalmology at the University of Hong Kong.

Dr. Geoffrey Lau from the Department of Biomedical Sciences at the City University of Hong Kong.

Dr. Wai Kit Chu from the Department of Ophthalmology and Visual Sciences at the Chinese University of Hong Kong.

Dr. Wenjun Xiong from the Department of Biomedical Sciences at the City University of Hong Kong

Dr. Rosa Chan from the Department of Electronic Engineering at the City University of Hong Kong.

Jeremiah Palmerston from Dr. Rosa Chan’s group.

Fai and Logan also attended the International Conference of Vision & Eye Research (iCOVER) when they were in Hong Kong.

Fai and Logan with Dr. Chi Wai Do from the School of Optometry at the Hong Kong Polytechnic University and Dr. Amy Lo from the Department of Ophthalmology at the University of Hong Kong during the dinner ceremony of iCOVER.

Logan and Fai with Dr. Henry Chan from the School of Optometry at the Hong Kong Polytechnic University during the coffee break of iCOVER.

 

In May 2017, the Leung lab visited several collaborating groups in Asia and shared with them our research vision on using zebrafish to find new drugs for retinal degeneration. In this blog post, we will share some pictures of our visit to the Department of Ophthalmology at the Osaka University School of Medicine. We met our long-term collaborator Dr. Motokazu Tsujikawa. He is a co-mentor of Logan Ganzen, a graduate student in our laboratory. Logan is a recipient of the predoctoral award from the Indiana Clinical and Translational Sciences Institute. During our Osaka trip, he presented a talk entitled “Visual Motor Response of a Transgenic Retinitis Pigmentosa Zebrafish Model” to Dr. Tsujikawa.

 

Logan in front of a new Center for Medical Innovation and Translational Research.

Fai and Dr. Motokazu in his zebrafish facility in the Center of Medical Innovation and Translational Research.

The Center is beautifully designed with lots of open space.

Logan presented his latest findings to Dr. Motokazu, who served as a co-mentor in Logan’s CTSI predoctoral fellowship.

We also visited the daily operation of the ophthalmology clinic and Osaka University Hospital, and participated in the grand rounds of the local ophthalmologists. We experienced firsthand the passion of translational research from our Japanese colleagues.

Entrance hall of the medical building

A panoramic view at the top floor of the hospital.

We joined the grand rounds of the local ophthalmologists. Dr. Kohji Nishida welcomed the group and gave an opening speech.  Even though we did not speak Japanese, we witnessed their passion to improve clinical service through research.

Needless to say, we were also well-fed by Dr. Tsujikawa with the finest Japanese food, and took some time to visit Kyoto, a magnificent ancient city.

Dr. Motokazu fed us with delicious Japanese food!

A torii path at the Fushimi Inari Taisha in Kyoto.

Kinkaku-ji in Kyoto

Our research on zebrafish vision has been featured by Inés Laura Dawson from Draw Curiosity in her educational science video entitled “Is Animal Vision 20/20?”.

Logan Ganzen and Yuk Fai Leung attended the 2017 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) in Baltimore, MD from 2017-05-07 to 05-11. Logan presented a poster entitled “Visual Motor Response of a Transgenic Retinitis Pigmentosa Zebrafish Model”. They also attended several events to meet fellow researchers over the world. A few pictures of these events:

Dinner with zebrafish colleagues

Prof. Mark Tso from Wilmer Eye Institute sharing his life experience with his former students

Dinner with Dr. Mark Tso from the Wilmer Eye Institute.

Fai and Logan with Dr. Mark Tso from the Wilmer Eye Institute.

 

Dinner with Prof. Mark Tso and his former students.