I am preparing these reading materials for my class and strongly believe that you would be interested in and benefited by reading these articles.

These are a series of articles published in this issue of Nature Medicine about this year’s Lasker Awards, the most prestigious award for biomedical research in this country.

There is an introductory article written by the Chairman of the Awards Jury, Joseph Goldstein, on the importance of the findings and a great summary of wisdom on doing great research; this is followed by the articles written by the recipients that give a personal account on the discovery process. While there is no guarantee that one will succeed by following their recipe, but there is always a lesson to learn from these good scientists. In particular, how they persisted and determined to look for an answer over many years.


  1. Goldstein JL. How to win a Lasker? Take a close look at Bathers and Bulls. Nat Med. 2010 Oct;16(10):1091-6. PubMed PMID: 20930751.
  2. Coleman DL. A historical perspective on leptin. Nat Med. 2010Oct;16(10):1097-9. PubMed PMID: 20930752.
  3. Friedman JM. A tale of two hormones. Nat Med. 2010 Oct;16(10):1100-6. PubMedPMID: 20930753.
  4. Ferrara N. Vascular endothelial growth factor and age-related maculardegeneration: from basic science to therapy. Nat Med. 2010 Oct;16(10):1107-11.PubMed PMID: 20930754.
  5. Weatherall D. Thalassemia: the long road from the bedside through thelaboratory to the community. Nat Med. 2010 Oct;16(10):1112-5. PubMed PMID:20930755.

Leave a Reply