RESEARCH TOPICS

Basic Research

Function of the vesicle trafficking machinery

1B) New paradigms on cargo recognition and endocytic network assembly

CARGO RECOGNITION

Artificial neural network for the prediction of tyrosine-based sorting signal recognition by adaptor complexes. Mukherjee D, Hanna CB, Aguilar RC. J Biomed Biotechnol. 2012;2012:498031. doi: 10.1155/2012/498031.

Introduction to the analysis of the intracellular sorting information in protein sequences: from molecular biology to artificial neural networks. Aguilar RC. Methods Mol Biol. 2015;1260:1-16.

The Na+ pump Ena1 is a yeast Epsin-specific cargo requiring its ubiquitination/phosphorylation sites for internalization. Sen A, Hsieh WC, Hanna CB, Hsu CC, Pearson M 2nd, Tao WA, Aguilar RC. J Cell Sci. 2020 Jul 21:jcs.245415. doi: 10.1242/jcs.245415. 2013 Jun;22(6):755-61.

Purdue University Center for Cancer Research
Purdue University Institute for Drug Discovery
Purdue University Institute for Integrative Neuroscience
Purdue Institute of Inflammation, Immunology and Infectious Disease
Purdue University Center for Science of Information
PULSE