Elizabeth Taparowsky Publications


Karki, A., Humphrey, S. E., Steele, R. E., Hess, D. A., Taparowsky, E. J., and Konieczny, S. F. 2015. Silencing Mist1 gene expression is essential for recovery from acute pancreatitis. PLoS One 10:e0145724.

Kim, M. H., Taparowsky, E. J., and Kim, C. H. 2015. Retinoic acid differentially regulates the migration of innate lymphoid cell subsets to the gut. Immunity 43:107-119.

Yao, S., Buzo, B. F., Pham, D., Jiang, L., Taparowsky, E. J., Kaplan, M. H., and Sun, J. 2013. Interferon regulatory factor 4 sustains CD8+ T cell expansion and effector differentiation. Immunity 39:833-845.

Jabeen, R., Goswami, R., Awe, O., Kulkarni, A., Nguyen, E. T., Attenasio, A., Walsh, D., Olson, M. R., Kim, M. H., Tepper, R. S., Sun, J., Kim, C. H., Taparaowsky, E. J., Zhou, B., and Kaplan, M. H. 2013. Th9 cell development requires a BATF-regulated transcriptional network. J. Clin. Invest. 123:4641-4653.

Jordan-Williams, K. L., Poston, S., and Taparowsky, E. J. 2013. BATF regulates the development and function of IL-17 producing iNKT cells. BMC Immunol. 14:16. doi: 10.1186/1471-2172-14-16.

Wang, C., Thangamani, S., Kim, M., Gu, B.-H., Lee, J. H., Taparowsky, E. J. and Kim, C. H. 2013. BATF is required for normal expression of gut-homing receptors by T helper cells in response to retinoic acid. J. Exp. Med. 210:475-489.

Xiao, X., Balasubramanian, S., Liu, W., Chu, X., Wang, H., Taparowsky, E. J., Fu, Y.-X., Choi, Y., Walsh, M. C., and Li, X. C. 2012. OX40 signaling favors the induction of TH9 cells and airway inflammation. Nat. Immunol. 13:981-990.

Logan, M. R., Jordan-Williams, K. L., Poston, S., Liao, S., and Taparowsky, E. J. 2012. Overexpression of Batf induces an apoptotic defect and an associated lymphoproliferative disorder in mice. Cell Death Dis. e310. doi: 10.1038/cddis.2012.49.

Liao, J., Humphrey, S. E., Poston, S., Taparowsky, E. J. 2011. Batf promotes growth arrest and terminal differentiation of mouse myeloid leukemia cells. Mol Cancer Res. 9: 350-362.

Betz, B. C., Jordan-Williams, K. L., Wang, C., Kang, S. G., Liao, J., Logan, M. R., Kim, C. H., Taparowsky, B. J. 2010. Batf coordinates multiple aspects of B and T cell function required for a normal antibody response. J Exp Med. 207: 933-942.

Zullo, A. J., Benlagha, K., Bendelac, A., Taparowsky, E. J. 2007. Sensitivity of NK1.1-negative NKT cells to transgenic BATF defines a role for activator protein-1 in the expansion and maturation of immature NKT cells in the thymus. J Immunol. 178: 58-66. view article

Burton, R. A., Mattila, S., Taparowsky, E. J., Post, C. B. 2006. B-myc: N-terminal recognition of myc binding proteins. Biochemistry. 45: 9857-9865.

Deppmann, C. D., Alvania, R. S., Taparowsky, E. J. 2006. Cross-species Annotation of Basic Leucine Zipper Factor Interactions: Insight Into the Evolution of Closed Interaction Networks. Mol Biol Evol. 23: 1480-1492.

Liu, H., Deng, X., Shyu, Y. J., Li, J. J., Taparowsky, E. J., Hu, C. D. 2006. Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization. Embo J. 25: 1058-1069.

Thornton, T. M., Zullo, A. J., Williams, K. L., Taparowsky, E. J. 2006. Direct manipulation of activator protein-1 controls thymocyte proliferation in vitro. Eur J Immunol. 36: 160-169.

Tuveson, D. A., Zhu, L., Gopinathan, A., Willis, N. A., Kachatrian, L., Grochow, R., Pin, C. L., Mitin, N. Y., Taparowsky, E. J., Gimotty, P. A., Hruban, R. H., Jacks, T., Konieczny, S. F. 2006. Mist1-KrasG12D knock-in mice develop mixed differentiation metastatic exocrine pancreatic carcinoma and hepatocellular carcinoma. Cancer Res. 66: 242-247.

Vinson, C., Acharya, A., Taparowsky, E. J. 2006. Deciphering B-ZIP transcription factor interactions in vitro and in vivo. Biochim Biophys Acta. 1759: 4-12.

Zullo, A. J., Brutkiewicz, R. R., Taparowsky, E. J. 2006. Selective identification of Vα14i T cells using slide-immobilized, CD1d-antigen complexes. J Immunoassay Immunochem. 27: 207-212.

Mitin, N., Konieczny, S. F., Taparowsky, E. J. 2005. RAS and the RAIN/RasIP1 Effector. Methods Enzymol. 407: 322-335.

Deppmann, C. D., Acharya, A., Rishi, V., Wobbes, B., Smeekens, S., Taparowsky, E. J., Vinson, C. 2004. Dimerization specificity of all 67 B-ZIP motifs in Arabidopsis thaliana: a comparison to Homo sapiens B-ZIP motifs. Nucleic Acids Res. 32: 3435-3445.

Mitin, N. Y., Ramocki, M. B., Zullo, A. J., Der, C. J., Konieczny, S. F., Taparowsky, E. J. 2004. Identification and characterization of rain, a novel Ras-interacting protein with a unique subcellular localization. J Biol Chem. 279: 22353-22361.

Deppmann, C. D., Taparowsky, E. J. 2003. Reverse-polarity PAGE for examining DNA binding domain phosphorylation. Biotechniques. 34: 56-59.

Deppmann, C. D., Thornton, T. M., Utama, F. E., Taparowsky, E. J. 2003. Phosphorylation of BATF regulates DNA binding: a novel mechanism for AP-1 (activator protein-1) regulation. Biochem J. 374: 423-431.

Johansen, L. M., Deppmann, C. D., Erickson, K. D., Coffin, W. F., 3rd, Thornton, T. M., Humphrey, S. E., Martin, J. M., Taparowsky, E. J. 2003. EBNA2 and activated Notch induce expression of BATF. J Virol. 77: 6029-6040.

Williams, K. L., Zullo, A. J., Kaplan, M. H., Brutkiewicz, R. R., Deppmann, C. D., Vinson, C., Taparowsky, E. J. 2003. BATF transgenic mice reveal a role for activator protein-1 in NKT cell development. J Immunol. 170: 2417-2426.

Daumer, K. M., Taparowsky, E. J., Hall, D. J., Steinbeck, M. J. 2002. Transcription from the tartrate-resistant acid phosphatase promoter is negatively regulated by the Myc oncoprotein. J Bone Miner Res. 17: 1701-1709.

Senga, T., Iwamoto, T., Humphrey, S. E., Yokota, T., Taparowsky, E. J., Hamaguchi, M. 2002. Stat3-dependent induction of BATF in M1 mouse myeloid leukemia cells. Oncogene. 21: 8186-8191.

Wyzykowski, J. C., Winata, T. I., Mitin, N., Taparowsky, E. J., Konieczny, S. F. 2002. Identification of novel MyoD gene targets in proliferating myogenic stem cells. Mol Cell Biol. 22: 6199-6208.

Zelinski, D. P., Zantek, N. D., Walker-Daniels, J., Peters, M. A., Taparowsky, E. J., Kinch, M. S. 2002. Estrogen and Myc negatively regulate expression of the EphA2 tyrosine kinase. J Cell Biochem. 85: 714-720.

Mitin, N., Kudla, A. J., Konieczny, S. F., Taparowsky, E. J. 2001. Differential effects of Ras signaling through NFκB on skeletal myogenesis. Oncogene. 20: 1276-1286.

Williams, K. L., Nanda, I., Lyons, G. E., Kuo, C. T., Schmid, M., Leiden, J. M., Kaplan, M. H., Taparowsky, E. J. 2001. Characterization of murine BATF: a negative regulator of activator protein-1 activity in the thymus. Eur J Immunol. 31: 1620-1627.

Mitin, N., Ramocki, M. B., Konieczny, S. F., Taparowsky, E. J. 2001. Ras regulation of skeletal muscle differentiation and gene expression. Methods Enzymol. 333: 232-247.

Echlin, D. R., Tae, H. J., Mitin, N., Taparowsky, E. J. 2000. B-ATF functions as a negative regulator of AP-1 mediated transcription and blocks cellular transformation by Ras and Fos. Oncogene. 19: 1752-1763.

Meyerdierks, A., Denecke, B., Rohde, M., Taparowsky, E. J., Bottger, E. C. 1999. A cytoplasmic structure resembling large protein aggregates induced by interferons. J Histochem Cytochem. 47: 169-182.

Wang, X., Peters, M. A., Utama, F. E., Wang, Y., Taparowsky, E. J. 1999. The Adrenomedullin gene is a target for negative regulation by the Myc transcription complex. Mol Endocrinol. 13: 254-267.

Meyer, N. P., Johansen, L. M., Tae, H. J., Budde, P. P., Williams, K. L., Taparowsky, E. J. 1998. Genomic organization of human B-ATF, a target for regulation by EBV and HTLV-1. Mamm Genome. 9: 849-852.

Peters, M. A., Taparowsky, E. J. 1998. Target genes and cellular regulators of the Myc transcription complex. Crit Rev Eukaryot Gene Expr. 8: 277-296.

Ramocki, M. B., White, M. A., Konieczny, S. F., Taparowsky, E. J. 1998. A role for RalGDS and a novel Ras effector in the Ras-mediated inhibition of skeletal myogenesis. J Biol Chem. 273: 17696-17701.

Krylov, D., Kasai, K., Echlin, D. R., Taparowsky, E. J., Arnheiter, H., Vinson, C. 1997. A general method to design dominant negatives to B-HLHZip proteins that abolish DNA binding. Proc Natl Acad Sci U S A. 94: 12274-12279.

Nanda, I., Peters, M. A., Taparowsky, E. J., Sperling, K., Schmid, M. 1997. Assignment of the chicken MAX gene to chromosome 5p by fluorescence in situ hybridization. Cytogenet Cell Genet. 76: 229-232.

Olive, M., Krylov, D., Echlin, D. R., Gardner, K., Taparowsky, E., Vinson, C. 1997. A dominant negative to activation protein-1 (AP1) that abolishes DNA binding and inhibits oncogenesis. J Biol Chem. 272: 18586-18594.

Peters, M. A., Sollenberger, K. G., Kao, T. L., Taparowsky, E. J. 1997. A minimal regulatory region maintains constitutive expression of the max gene. Mol Cell Biol. 17: 1037-1048.

Ramocki, M. B., Johnson, S. E., White, M. A., Ashendel, C. L., Konieczny, S. F., Taparowsky, E. J. 1997. Signaling through mitogen-activated protein kinase and Rac/Rho does not duplicate the effects of activated Ras on skeletal myogenesis. Mol Cell Biol. 17: 3547-3555.

Weyman, C. M., Ramocki, M. B., Taparowsky, E. J., Wolfman, A. 1997. Distinct signaling pathways regulate transformation and inhibition of skeletal muscle differentiation by oncogenic Ras. Oncogene. 14: 697-704.

Krylov, D., Echlin, D. R., Taparowsky, E. J., Vinson, C. 1997. Design of dominant negatives to bHLHZip proteins that inhibit DNA binding. Curr Top Microbiol Immunol. 224: 169-177.

Johnson, S. E., Wang, X., Hardy, S., Taparowsky, E. J., Konieczny, S. F. 1996. Casein kinase II increases the transcriptional activities of MRF4 and MyoD independently of their direct phosphorylation. Mol Cell Biol. 16: 1604-1613.

Wang, X., Johansen, L. M., Tae, H. J., Taparowsky, E. J. 1996. IFP 35 forms complexes with B-ATF, a member of the AP1 family of transcription factors. Biochem Biophys Res Commun. 229: 316-322.

Dorsey, M. J., Tae, H. J., Sollenberger, K. G., Mascarenhas, N. T., Johansen, L. M., Taparowsky, E. J. 1995. B-ATF: a novel human bZIP protein that associates with members of the AP-1 transcription factor family. Oncogene. 11: 2255-2265.

Kong, Y., Johnson, S. E., Taparowsky, E. J., Konieczny, S. F. 1995. Ras p21Val inhibits myogenesis without altering the DNA binding or transcriptional activities of the myogenic basic helix-loop-helix factors. Mol Cell Biol. 15: 5205-5213.

Min, S., Crider-Miller, S. J., Taparowsky, E. J. 1994. The transcription activation domains of v-Myc and VP16 interact with common factors required for cellular transformation and proliferation. Cell Growth Differ. 5: 563-573.

Sollenberger, K. G., Kao, T. L., Taparowsky, E. J. 1994. Structural analysis of the chicken max gene. Oncogene. 9: 661-664.

Crowe, R. A., Taparowsky, E. J., Crane, F. L. 1993. Ha-ras stimulates the transplasma membrane oxidoreductase activity of C3H10T1/2 cells. Biochem Biophys Res Commun. 196: 844-850.

Min, S., Mascarenhas, N. T., Taparowsky, E. J. 1993. Functional analysis of the carboxy-terminal transforming region of v-Myc: binding to Max is necessary, but not sufficient, for cellular transformation. Oncogene. 8: 2691-2701.

Mauro, L. J., Woodford-Thomas, T. A., Pot, D. A., Taparowsky, E. J., Dixon, J. E. 1993. Targeting of an intracellular tyrosine phosphatase: mechanisms and functional significance. Adv Prot Phosphatases. 7: 393-411.

Davenport, E. A., Taparowsky, E. J. 1992. Basal levels of max are sufficient for the cotransformation of C3H10T1/2 cells by ras and myc. Exp Cell Res. 202: 532-540.

Min, S., Taparowsky, E. J. 1992. v-Myc, but not Max, possesses domains that function in both transcription activation and cellular transformation. Oncogene. 7: 1531-1540.

Vaidya, T. B., Rhodes, S. J., Moore, J. L., Sherman, D. A., Konieczny, S. F., Taparowsky, E. J. 1992. Isolation and structural analysis of the rat MyoD gene. Gene. 116: 223-230.

Vaidya, T. B., Weyman, C. M., Teegarden, D., Ashendel, C. L., Taparowsky, E. J. 1991. Inhibition of myogenesis by the H-ras oncogene: implication of a role for protein kinase C. J Cell Biol. 114: 809-820.

Davenport, E. A., Taparowsky, E. J. 1990. Novel phenotype of C3H 10T1/2 fibroblasts cotransfected with the c-Ha-ras and adenovirus 5 E1A oncogenes. Mol Carcinog. 3: 83-92.

Enkemann, S. A., Konieczny, S. F., Taparowsky, E. J. 1990. Adenovirus 5 E1A represses muscle-specific enhancers and inhibits expression of the myogenic regulatory factor genes, MyoD1 and myogenin. Cell Growth Differ. 1: 375-382.

Teegarden, D., Taparowsky, E. J., Kent, C. 1990. Altered phosphatidylcholine metabolism in C3H10T1/2 cells transfected with the Harvey-ras oncogene. J Biol Chem. 265: 6042-6047.

Konieczny, S. F., Drobes, B. L., Menke, S. L., Taparowsky, E. J. 1989. Inhibition of myogenic differentiation by the H-ras oncogene is associated with the down regulation of the MyoD1 gene. Oncogene. 4: 473-481.

Vaidya, T. B., Rhodes, S. J., Taparowsky, E. J., Konieczny, S. F. 1989. Fibroblast growth factor and transforming growth factor-β repress expression of the myogenic regulatory gene MyoD1. Mol Cell Biol. 9: 3576-3579.

Davenport, E. A., Drobes, B. L., Menke, S. L., Vaidya, T. B., Taparowsky, E. J. 1988. Cooperation of oncogenes in the multistep transformation of established fibroblasts in culture. Anticancer Res. 8: 959-969.

Weyman, C. M., Taparowsky, E. J., Wolfson, M., Ashendel, C. L. 1988. Partial down-regulation of protein kinase C in C3H 10T 1/2 mouse fibroblasts transfected with the human Ha-ras oncogene. Cancer Res. 48: 6535-6541.

Taparowsky, E. J., Heaney, M. L., Parsons, J. T. 1987. Oncogene-mediated multistep transformation of C3H10T1/2 cells. Cancer Res. 47: 4125-4129.

Fasano, O., Aldrich, T., Tamanoi, F., Taparowsky, E., Furth, M., Wigler, M. 1984. Analysis of the transforming potential of the human H-ras gene by random mutagenesis. Proc Natl Acad Sci U S A. 81: 4008-4012.

Fasano, O., Taparowsky, E., Fiddes, J., Wigler, M., Goldfarb, M. 1983. Sequence and structure of the coding region of the human H-ras-1 gene from T24 bladder carcinoma cells. J Mol Appl Genet. 2: 173-180.

Shimizu, K., Birnbaum, D., Ruley, M. A., Fasano, O., Suard, Y., Edlund, L., Taparowsky, E., Goldfarb, M., Wigler, M. 1983. Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1. Nature. 304: 497-500.

Taparowsky, E., Shimizu, K., Goldfarb, M., Wigler, M. 1983. Structure and activation of the human N-ras gene. Cell. 34: 581-586.

Taparowsky, E., Suard, Y., Fasano, O., Shimizu, K., Goldfarb, M., Wigler, M. 1982. Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change. Nature. 300: 762-765.

Taparowsky, E. J., Gerbi, S. A. 1982. Structure of 1.71 lb gm/cm(3) bovine satellite DNA: evolutionary relationship to satellite I. Nucleic Acids Res. 10: 5503-5515.

Taparowsky, E. J., Gerbi, S. A. 1982. Sequence analysis of bovine satellite I DNA (1.715 gm/cm3). Nucleic Acids Res. 10: 1271-1281.

Book Section

Mitin, N., Ramocki, M. B., Konieczny, S. F., Taparowsky, E. J. 2001. Ras regulation of skeletal muscle differentiation and gene expression.  In Methods of Enzymology, Regulators and Effectors of Small GTPases.  Balch, W. E., Der, C. J., and Hall, A. (eds), Academic Press . Methods Enzymol. 333: 232-247.


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