Angeline Lyon Publications


Lyon, A.M., Begley, J.A., Manett, T.D., and Tesmer, J.J.G., Molecular Mechanisms of PLCβ3 Autoinhibition, Structure 2014, 22, , 1844-1854.

Lyon, A.M., Dutta, S., Boguth, C.A., Skiniotis, G., and Tesmer, J.J.G., Structure of Full-Length Phospholipase C β3 in Complex with Gαq Reveals Functional Interfaces of its Cterminal Coiled-Coil Domain, Nat. Struct. Mol. Biol. 2013, 20, 355-362.

Lyon, A.M., Tesmer, V.M., Dhamsania, V. D., Thal, D.M., Gutierrez, J., Chowdhury, S., Suddala, K., Northup, J.K., and Tesmer, J.J.G., An Autoinhibitory Helix in the C-Terminal Region of Phospholipase Cβ Represses Basal Activity and Mediates Gαq Activation, Nat. Struct. Mol. Biol. 2011, 18, 999-1005.

Lyon, A.M., Dutta, S., Boguth, C.A., Skiniotis, G., and Tesmer, J.J.G., Full-length Gα(q)-phospholipase C-β3 structure reveals interfaces of the C-terminal coiled-coil domain. PMCID: PMC3594540, Nat. Struct. Mol. Biol.2013, 20, 355-362.

Lyon, A.M. and Tesmer J. J. G., Structural insights into phospholipase C-β function. PMID: 23880553, Mol. Pharm.2013, 84, 488-500.                                           

Lyon, A.M., Reveal, B.S., Macdonald, P.M., Hoffman, D.W., Bruno protein contains an expanded RNA recognition motif. PMID: 19919093, Biochemistry, 2009, 48, 12202-12.                                          

Lyon, A.M., Taylor, V. G., and Tesmer, J. J. G., Strike a pose: Gαq complexes at the membrane. PMID: 24287282, Trends in Pharmacological Sciences. 2014, 35, 23-30.


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