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Associate Professor
LILY 1-225
Phone: 765-494-1601

Paschou Lab: Link

I work at the intersection of human population genetics, statistical analysis and genomic medicine, and my research interests lie in two main areas: first, I study the genetic basis of complex disorders in diverse human populations aiming to translate research findings into clinical applications and, second, using novel methods for large-scale data analysis, I investigate human genomic variation and population genetic relationships around the world.

Towards the first goal, a major focus of my research is the elucidation of the genetic background of neurodevelopmental phenotypes, such as Gilles de la Tourette Syndrome, autism, obsessive compulsive disorder and attention deficit hyperactivity disorder. I study genomewide datasets and I have a leading role in multiple large-scale collaborative efforts such as the EMTICS and TS-EUROTRAIN consortia. At the same time, working with neuropathologists and analyzing whole genome sequencing data, I also investigate the potential link between neurodegeneration and neurodevelopment.

On the other hand, working towards the decomposition of human genetic variation around the world, I investigate human evolution and the migration patterns of the human population across the globe and in particular population movements around the Mediterranean basin (GENOMAP.GR project). Interdisciplinarity is an important aspect of my work and I place particular emphasis on transferring algorithms and methodology from the fields of Computer Science and Applied Mathematics to population genetics and medical genetics. In an era of Big Data and the ability to mine the genome of hundreds of thousands of individuals, such approaches pave the way towards the direction of personalized medicine.


Links to selected press-releases about our work can be found here.



2005             Diplomate of the American Board of Medical Genetics (August 2005) - Clinical Molecular Genetics Specialty. Yale University School of Medicine, Department of Genetics - Medical Genetics Training Program (2002-2005)

2002-2005   Postdoctoral Training, Yale University School of Medicine, Department of Genetics (Supervisor: Kenneth K. Kidd)

1999-2002   National University of Athens, PhD

1999-2000   University of Oxford, “Wellcome Trust Centre for Human Genetics” – Training Fellowship



2015             Associate Professor of Population Genetics, (tenured) Democritus University of Thrace, Department of Molecular Biology and Genetics

2010-2015   Assistant Professor of Population Genetics, Democritus University of Thrace, Department of Molecular Biology and Genetics

2011             Adjunct Investigator, National Institute of Child Health and Human Development, Bethesda, USA

2005-2010   Lecturer in Population Genetics, Democritus University of Thrace, Department of Molecular Biology and Genetics

2007             Visiting Scientist, Center for Neurobehavioral Genetics, Medical School, University of California Los Angeles, USA

2006             Visiting Specialist, Institute for Human Genetics, University of California San Francisco, USA

2002-2005   Postdoctoral Fellow, Department of Genetics, Yale University School of Medicine, USA

1999-2002   Research Associate, National University of Athens - European Cooperation Project: “Diabetes Prediction and Prevention - DIPP DEMO Project”


Boards of scientific societies

2014-2017   Board Member European Society for the Study of Tourette Syndrome (ESSTS)

2011-2014   Chair of the European Society for the Study of Tourette Syndrome (ESSTS)

2011-2012   Treasurer of the Board of Directors - Hellenic Association for Medical Genetics

Editorial boards

2009-today  Academic Editor - Journal of Medical Genetics

2011-today  Review Editor -  Frontiers in Evolutionary and Population Genetics

2012-today  Academic Editor - PLOS ONE

2015             Editor – Frontiers Research Topic: The Neurobiology and Genetics of Gilles de la Tourette Syndrome


2015             Latsis Foundation – Award for 2015 Scientific Studies by Young Researchers

2014             ARISTEIA II – Excellence Career Award, co-funded by Greece and the European Union

2005             Hellenic Endocrine Society, 1st research grant award



Links to our papers can be found here.


Professional Faculty Research

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