Publications
[ 2013 | 2012 | 2011 | 2010 | 2008 ]
pre-Purdue era [ 2007 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999]
2013
Zhang LY, Cho J, Ptak D, Leung YF. The role of egr1 in early zebrafish retinogenesis. PLOS ONE. 2013; 8(2): e56108. [PubMed][Full text][pdf]
Li Z, Zhang LY, Leung YF. Use of the zebrafish model to study refractive error. Expert Rev Ophthalmol. 2013; 8(1):1-3. (Invited Editorial Article) [Full text][pdf]
2012
Zhang LY, Chong L, Cho J, Liao PC, Shen F, Leung YF. Drug Screening to Treat Early-Onset Eye Diseases: Can Zebrafish Expedite the Discovery? Asia-Pac J Ophthalmol 2012; 1:374-383. (Invited Review) [Full text][pdf]
- Featured in the American Academy of Ophthalmology Academy Express - Asia-Pacific Edition, December 15, 2012
- Editor's Picks, Asia-Pac J Ophthalmol.
Li Z, Ptak D, Zhang LY, Walls EK, Zhong W, Leung YF. Phenylthiourea specifically reduces zebrafish eye size. PLoS ONE. 2012;7(6):e40132. [PubMed][Full text][pdf]
Zhang YQ, Yang YF, Trujillo CM, Zhong W, Leung YF. The expression of irx7 in the inner nuclear layer of zebrafish retina is essential for a proper development of both inner and outer nuclear layers and formation of retinal lamination. PLoS ONE. 2012;7(4): e36145. [PubMed][Full text][pdf]
Hensley MR, Hassenplug E, McPhail R, Leung YF. ZeBase: An open-source relational database for zebrafish laboratories. Zebrafish. 2012;9(1):44-9. [PubMed][pdf][link to website]
2011
Hensley MR, Emran F, Bonilla S, Zhang L, Zhong W, Grosu P, Dowling JE, Leung YF. Cellular Expression of Smarca4 (Brg1)-regulated Genes in Zebrafish Retinas. BMC Dev Biol. 2011 Jul 14;11(1):45. [PubMed][Full text][pdf]
2010
Zhang L, Leung YF. Microdissection of Zebrafish Embryonic Eye Tissues. J. Vis. Exp. 2010; 40. pii: 2028. [PubMed][pdf] [Flash Video]
Hensley MR, Leung YF. A Convenient Dry Feed for Raising Zebrafish Larvae. Zebrafish. 2010; 7:219-31. [PubMed][pdf][Supp. Materials]
2008
Leung, Y.F., Ma, P., Link, B.A., Dowling, J.E. 2008. Factorial microarray analysis of zebrafish retinal development. Proc Natl Acad Sci U S A. 105. 35. 12909-12914. [PubMed][pdf] [Supplementary Information][Data in GEO]
2007
Leung, Y. F., Ma, P., Dowling, J. E. 2007. Gene expression profiling of zebrafish embryonic retinal pigment epithelium in vivo. Invest Ophthalmol Vis Sci. 48. 2. 881-890. [PubMed][pdf][Supplementary Information]
2005
Leung, Y. F., Dowling, J. E. 2005. Gene expression profiling of zebrafish embryonic retina. Zebrafish. 2. 4. 269-283. [PubMed][pdf][Data in GEO]
2004
Fan, B. J., Leung, Y. F., Pang, C. P., Baum, L., Tam, O. S., Wang, N., Lam, S. C. 2004. Single nucleotide polymorphisms of the myocilin gene in primary open-angle glaucoma patients. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 21. 1. 70-73. [PubMed]
Fan, B. J., Leung, Y. F., Pang, C. P., Fan, D. S., Wang, D. Y., Tong, W. C., Tam, P. O., Chua, J. K., Lau, T. C., Lam, D. S. 2004. Polymorphisms in the myocilin promoter unrelated to the risk and severity of primary open-angle glaucoma. J Glaucoma. 13. 5. 377-384. [PubMed]
Fan, B. J., Leung, Y. F., Wang, N., Lam, S. C., Liu, Y., Tam, O. S., Pang, C. P. 2004. Genetic and environmental risk factors for primary open-angle glaucoma. Chin Med J (Engl). 117. 5. 706-710. [PubMed][pdf]
2003
Fan BJ, Leung YF. Beginning microarray data analysis for biologists. J Cell Sci. 2003; 116: 1649-1650. [Full text][pdf]
Lam, D. S., Lee, W. S., Leung, Y. F., Tam, P. O., Fan, D. S., Fan, B. J., Pang, C. P. 2003. TGFbeta-induced factor: a candidate gene for high myopia. Invest Ophthalmol Vis Sci. 44. 3. 1012-1015. [PubMed][pdf]
Lam, D. S., Tam, P. O., Fan, D. S., Baum, L., Leung, Y. F., Pang, C. P. 2003. Familial high myopia linkage to chromosome 18p. Ophthalmologica. 217. 2. 115-118. [PubMed]
Leung YF. The Essence of Interdisciplinary Research--Mindset Matters. Science. 2003. [Full text]
Leung, Y. F., Cavalieri, D. 2003. Fundamentals of cDNA microarray data analysis. Trends Genet. 19. 11. 649-659. [PubMed][Full text][pdf]
Leung, Y. F., Fan, B. J., Lam, D. S., Lee, W. S., Tam, P. O., Chua, J. K., Tham, C. C., Lai, J. S., Fan, D. S., Pang, C. P. 2003. Different optineurin mutation pattern in primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 44. 9. 3880-3884. [PubMed][pdf]
Leung, Y. F., Tam, P. O., Lee, W. S., Lam, D. S., Yam, H. F., Fan, B. J., Tham, C. C., Chua, J. K., Pang, C. P. 2003. The dual role of dexamethasone on anti-inflammation and outflow resistance demonstrated in cultured human trabecular meshwork cells. Mol Vis. 9. 425-439. [PubMed][pdf]
2002
Leung YF, Lam DS, Pang CP. Microarray software review. In: A practical approach to microarray data analysis. D.P. Berrar, W. Dubitzky and M. Granzow, (Eds.), Kluwer academic, 2002. [Full text]
Leung, Y. F. 2002. Unravelling the mystery of microarray data analysis. Trends Biotechnol. 20. 9. 366-368. [PubMed]
Leung YF. 2002. Microarray data analysis for dummies ... and experts too? Trends Biochem Sci. 2002; 27:433-434. [Full text][pdf]
Leung, Y. F., Pang, C. P. 2002. EYE on bioinformatics: dissecting complex disease traits in silico. Appl Bioinformatics. 1. 2. 69-80. [PubMed]
Pang, C. P., Leung, Y. F., Fan, B., Baum, L., Tong, W. C., Lee, W. S., Chua, J. K., Fan, D. S., Liu, Y., Lam, D. S. 2002. TIGR/MYOC gene sequence alterations in individuals with and without primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 43. 10. 3231-3235. [PubMed][pdf]
2001
Leung YF, Pang CP, Browne K. Guide to microarray hardware - a researcher perspective. Lab-on-a-chip.com 2001 [Full text][table of array scanner][table of manual scanner][table of automatic arrayers]
Leung, Y. F., Lam, D. S., Pang, C. P. 2001. When drugs development meets genomics. Pharmacogenomics J. 1. 4. 237-238. [PubMed]
Leung, Y. F., Lam, D. S., Pang, C. P. 2001. In silico biology: observation, modeling, hypothesis and verification. Trends Genet. 17. 11. 622-623. [PubMed]
Leung, Y. F., Lam, D. S., Pang, C. P. 2001. The miracle of microarray data analysis. Genome Biol. 2. 9. REPORTS4021. [PubMed][pdf]
Leung, Y. F., Pang, C. P. 2001. Trends in proteomics. Trends Biotechnol. 19. 12. 480-482. [PubMed]
Leung, Y. F., Pang, C. P. 2001. All aboard the chip! Trends Biotechnol. 19. 11. 430-431. [PubMed]
Leung, Y. F., Tam, P. O., Tong, W. C., Baum, L., Choy, K. W., Lam, D. S., Pang, C. P. 2001. High-throughput conformation-sensitive gel electrophoresis for discovery of SNPs. Biotechniques. 30. 2. 334-335, 338-340. [PubMed]
2000
Lam, D. S., Leung, Y. F., Chua, J. K., Baum, L., Fan, D. S., Choy, K. W., Pang, C. P. 2000. Truncations in the TIGR gene in individuals with and without primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 41. 6. 1386-1391. [PubMed][pdf]
Leung, Y. F., Baum, L., Lam, D. S., Fan, D. S., Chua, J. K., Pang, C. P. 2000. Absence of trabecular meshwork-inducible stretch response (TISR)/oculomedin gene and proximal promoter mutation in primary open angle glaucoma patients. Hum Genet. 107. 4. 404-405. [PubMed]
Leung, Y. F., Tam, P. O., Baum, L., Chan, W. M., Lam, D. S., Pang, C. P. 2000. Cost savings using automated DNA sequencing. Biotechniques. 29. 3. 544. [PubMed]
Leung, Y. F., Tam, P. O., Baum, L., Lam, D. S., Pang, C. C. 2000. TIGR/MYOC proximal promoter GT-repeat polymorphism is not associated with myopia. Hum Mutat. 16. 6. 533. [PubMed]
Pang, C. P., Leung, Y. F., Chua, J. K., Baum, L., Fan, D. S., Lam, D. S. 2000. Novel TIGR sequence alteration Val53Ala. Hum Mutat. 15. 1. 122. [PubMed]
1999
Baum, L., Pang, C. P., Fan, D. S., Poon, P. M., Leung, Y. F., Chua, J. K., Lam, D. S. 1999. Run-on mutation and three novel nonsense mutations identified in the PAX6 gene in patients with aniridia. Hum Mutat. 14. 3. 272-273. [PubMed]