Development and Disease

Publications

 

Julia Kirshner

 

Journal

Kirshner, J., Thulien, K. J., Kriangkum, J., Motz, S., Belch, A. R., Pilarski, L. M. 2011. In a patient with biclonal Waldenstrom macroglobulinemia only one clone expands in three-dimensional culture and includes putative cancer stem cells. Leukemia & Lymphoma. 52: 285-289.

Gunn, E. J., Williams, J. T., Huynh, D. T., Iannotti, M. J., Han, C., Barrios, F. J., Kendall, S., Glacking, C. A., Colby, D. A., Kirshner, J. 2011. The natural products parthenolide and andrographolide exhibit anti-cancer stem cell activity in multiple myeloma. Leukemia & Lymphoma. 1-13. (doi: 10.3109/10428194.2011.555891) .

Riofski, M. V., John, J. P., Zheng, M. M., Kirshner, J., Colby, D. A. 2011. Exploiting the facile release of trifluoroacetate for the α-methylenation of the sterically hindered carbonyl groups on (+)-sclareolide and (-)-eburnamonine. J Org Chem. IN PRESS.
(dx.doi.org/10.1021/jo102114). view article

Tancred, T. M., Belch, A. R., Reiman, T., Pilarski, L. M., Kirshner, J. 2009. Altered expression of fibronectin and collagens I and IV in multiple myeloma and monoclonal gammopathy of undetermined significance. JHC. 57: 239-247. view article

Kirshner, J., Thulien, K. J., Martin, L. D., Debes Marun, C., Reiman, T., Belch, A. R., Pilarski, L. M. 2008. A unique three-dimensional model for evaluating the impact of therapy on multiple myeloma. Blood. 112: 2935-2945. view article

Chen, C. J., Kirshner, J., Sherman, M. A., Hu, W., Nguyen, T., Shively, J. E. 2007. Mutation analysis of the short cytoplasmic domain of the cell-cell adhesion molecule CEACAM1 identifies residues that orchestrate actin binding and lumen formation. J Biol Chem. 282: 5749-5760. view article

Andarawewa, K. L., Kirshner, J., Mott, J. D., Barcellos-Hoff, M. H. 2007. "TGFβ: Roles in DNA damage responses. In S. B. Jakowlew (ed), Transforming Growth Factor-Beta in Cancer Therapy. Vol. 2. Humana Press, Inc..

Kirshner, J., Jobling, M. F., Pajares, M. J., Ravani, S. A., Glick, A. B., Lavin, M. J., Koslov, S., Shiloh, Y., Barcellos-Hoff, M. H. 2006. Inhibition of transforming growth factor-β1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress. Cancer Res. 66: 10861-10869. view article

Kirshner, J., Hardy, J., Wilczynski, S., Shively, J. E. 2004. Cell-cell adhesion molecule CEACAM1 is expressed in normal breast and milk and associates with β1 integrin in a 3D model of morphogenesis. J Mol Histol. 35: 287-299. view article

Schumann, D., Huang, J., Clarke, P. E., Kirshner, J., Tsai, S. W., Schumaker, V. N., Shively, J. E. 2004. Characterization of recombinant soluble carcinoembryonic antigen cell adhesion molecule 1. Biochem Biophys Res Commun. 318: 227-233. view article

Kirshner, J., Chen, C. J., Liu, P., Huang, J., Shively, J. E. 2003. CEACAM1-4S, a cell-cell adhesion molecule, mediates apoptosis and reverts mammary carcinoma cells to a normal morphogenic phenotype in a 3D culture. Proc Natl Acad Sci U S A. 100: 521-526. view article

Kirshner, J., Schumann, D., Shively, J. E. 2003. CEACAM1, a cell-cell adhesion molecule, directly associates with annexin II in a three-dimensional model of mammary morphogenesis. J Biol Chem. 278: 50338-50345. view article

Patent

Kirshner, J, Pilarski, L. M. 2007. A novel model for evaluation of therapeutics in cancer stem cells. U.S. Patent  #61/000751, preliminary filing 10/29/2007.