Development and Disease

Publications

 

Yuk Fai Leung

 

Journal

Zhang Y, Yang Y, Trujillo C, Zhong W, Leung YF. The expression of irx7 in the inner nuclear layer of zebrafish retina is essential for a proper retinal development and lamination. PLoS One. 2012;7(4):e36145.

Li Z, Ptak D, Zhang L, Walls EK, Zhong W, Leung YF. Phenylthiourea specifically reduces zebrafish eye size. PLoS One. 2012;7(6):e40132.

Hensley MR, Hessenplug E, McPhail R, Leung YF. ZeBase: An open-source relational database for zebrafish laboratories. Zebrafish. 2012 Mar;9(1):44-9.

Hensley, M. R., Emran, F., Bonilla, S., Zhang, L., Zhong, W., Grosu, P., Dowling, J. E., Leung, Y. F. 2011. Cellular expression of Smarca4 (Brg1)-regulated genes in zebrafish retinas. BMC Develomental Biology. 45: 11. Pubmed PMID:21756345; PubMed Central PMCID: PMC3155967.

Hensley, MR, Leung, YF. 2010. A Convenient Dry Feed for Raising Zebrafish Larvae. Zebrafish. 7: 219-231.

Zhang, L, Leung, YF. 2010. Microdissection of Zebrafish Embryonic Eye Tissues. J. Vis. Exp. 40: pii: 2028.

Leung YF, Ma P, Link BA, Dowling JE. 2008. Factorial microarray analysis of zebrafish retinal development. Proc Natl Acad Sci U S A. 105(35): 12909-14.

Leung, Y. F., Ma, P., Dowling, J. E. 2007. Gene expression profiling of zebrafish embryonic retinal pigment epithelium in vivo. Invest Ophthalmol Vis Sci. 48: 881-890.

Leung, Y. F., Dowling, J. E. 2005. Gene expression profiling of zebrafish embryonic retina. Zebrafish. 2: 269-283.

Fan, B. J., Leung, Y. F., Pang, C. P., Baum, L., Tam, O. S., Wang, N., Lam, S. C. 2004. Single nucleotide polymorphisms of the myocilin gene in primary open-angle glaucoma patients. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 21: 70-73.

Fan, B. J., Leung, Y. F., Pang, C. P., Fan, D. S., Wang, D. Y., Tong, W. C., Tam, P. O., Chua, J. K., Lau, T. C., Lam, D. S. 2004. Polymorphisms in the myocilin promoter unrelated to the risk and severity of primary open-angle glaucoma. J Glaucoma. 13: 377-384.

Fan, B. J., Leung, Y. F., Wang, N., Lam, S. C., Liu, Y., Tam, O. S., Pang, C. P. 2004. Genetic and environmental risk factors for primary open-angle glaucoma. Chin Med J (Engl). 117: 706-710.

Lam, D. S., Lee, W. S., Leung, Y. F., Tam, P. O., Fan, D. S., Fan, B. J., Pang, C. P. 2003. TGFbeta-induced factor: a candidate gene for high myopia. Invest Ophthalmol Vis Sci. 44: 1012-1015.

Lam, D. S., Tam, P. O., Fan, D. S., Baum, L., Leung, Y. F., Pang, C. P. 2003. Familial high myopia linkage to chromosome 18p. Ophthalmologica. 217: 115-118.

Leung, Y. F., Cavalieri, D. 2003. Fundamentals of cDNA microarray data analysis. Trends Genet. 19: 649-659.

Leung, Y. F., Fan, B. J., Lam, D. S., Lee, W. S., Tam, P. O., Chua, J. K., Tham, C. C., Lai, J. S., Fan, D. S., Pang, C. P. 2003. Different optineurin mutation pattern in primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 44: 3880-3884.

Leung, Y. F., Tam, P. O., Lee, W. S., Lam, D. S., Yam, H. F., Fan, B. J., Tham, C. C., Chua, J. K., Pang, C. P. 2003. The dual role of dexamethasone on anti-inflammation and outflow resistance demonstrated in cultured human trabecular meshwork cells. Mol Vis. 9: 425-439.

Leung, Y. F. 2002. Unravelling the mystery of microarray data analysis. Trends Biotechnol. 20: 366-368.

Leung, Y. F., Pang, C. P. 2002. EYE on bioinformatics: dissecting complex disease traits in silico. Appl Bioinformatics. 1: 69-80.

Pang, C. P., Leung, Y. F., Fan, B., Baum, L., Tong, W. C., Lee, W. S., Chua, J. K., Fan, D. S., Liu, Y., Lam, D. S. 2002. TIGR/MYOC gene sequence alterations in individuals with and without primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 43: 3231-3235.

Leung, Y. F., Lam, D. S., Pang, C. P. 2001. When drugs development meets genomics. Pharmacogenomics J. 1: 237-238.

Leung, Y. F., Lam, D. S., Pang, C. P. 2001. In silico biology: observation, modeling, hypothesis and verification. Trends Genet. 17: 622-623.

Leung, Y. F., Lam, D. S., Pang, C. P. 2001. The miracle of microarray data analysis. Genome Biol. 2: REPORTS4021.

Leung, Y. F., Pang, C. P. 2001. Trends in proteomics. Trends Biotechnol. 19: 480-482.

Leung, Y. F., Pang, C. P. 2001. All aboard the chip!. Trends Biotechnol. 19: 430-431.

Leung, Y. F., Tam, P. O., Tong, W. C., Baum, L., Choy, K. W., Lam, D. S., Pang, C. P. 2001. High-throughput conformation-sensitive gel electrophoresis for discovery of SNPs. Biotechniques. 30: 334-335, 338-340.

Lam, D. S., Leung, Y. F., Chua, J. K., Baum, L., Fan, D. S., Choy, K. W., Pang, C. P. 2000. Truncations in the TIGR gene in individuals with and without primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 41: 1386-1391.

Leung, Y. F., Baum, L., Lam, D. S., Fan, D. S., Chua, J. K., Pang, C. P. 2000. Absence of trabecular meshwork-inducible stretch response (TISR)/oculomedin gene and proximal promoter mutation in primary open angle glaucoma patients. Hum Genet. 107: 404-405.

Leung, Y. F., Tam, P. O., Baum, L., Chan, W. M., Lam, D. S., Pang, C. P. 2000. Cost savings using automated DNA sequencing. Biotechniques. 29: 544.

Leung, Y. F., Tam, P. O., Baum, L., Lam, D. S., Pang, C. C. 2000. TIGR/MYOC proximal promoter GT-repeat polymorphism is not associated with myopia. Hum Mutat. 16: 533.

Pang, C. P., Leung, Y. F., Chua, J. K., Baum, L., Fan, D. S., Lam, D. S. 2000. Novel TIGR sequence alteration Val53Ala. Hum Mutat. 15: 122.

Baum, L., Pang, C. P., Fan, D. S., Poon, P. M., Leung, Y. F., Chua, J. K., Lam, D. S. 1999. Run-on mutation and three novel nonsense mutations identified in the PAX6 gene in patients with aniridia. Hum Mutat. 14: 272-273.