Department of Biological Sciences

BIOL 39500 Macromolecules

Session Offered:

Fall Credit 3.0

Prerequisites:

BIOL 23100 or 27000 and BIOL 24100 or 28000

Description:

The course focuses on the comprehensive understanding of macromolecules by providing an introduction to: the types of macromolecules; the biophysical and biochemical properties of macromolecules; how biophysical and biochemical properties are determined; how these physicochemical properties are exploited in various biotechniques. In addition, a brief introduction to methods used to determine the structures of macromolecules and supramolecular assemblies will be presented. Next, the knowledge gained will be exploited to understand the physicochemical basis of structure-function relationships in macromolecules. By providing basic knowledge on macromolecules, the course will prepare students for more advanced and specialized courses.

A problem-driven teaching scheme will be adopted to address the properties of macromolecules such as chemical composition, concentration, solubility, mass, size, density, charge, color, absorption, fluorescence, energy, stability, folding, conformation, force, primary sequence, secondary structure, tertiary structure, macromolecular interaction and formation of complexes. The emphasis will be on how macromolecular properties influence structure function relationships, in addition to biophysical methods to determine these properties. Case studies and historical milestones will be used to illustrate these points.

Instructor(s):

Clark Gedney and Wen Jiang

Clark Gedney and Wen Jiang

E-mail:

cgedney@purdue.edu
jiang12@purdue.edu

Textbook(s):

˜No textbook required for this course  Lecture Notes from Instructors.~

Notes:

Exam information is available on-line via:
https://roomschedule.mypurdue.purdue.edu/Timetabling/exams.do

Course Format:

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