Department of Biological Sciences

BIOL 51700 Molecular Biology: Proteins

Session Offered:

Spring Credit 2.0

Prerequisites:

BCHM 56100 or CHM 53300 or 37200 or 37300 or BIOL 23000 and BME 20100.   May not be enrolled as the following classifications: Freshman 0-14 hours, Freshman 15-29 hours, Sophomore 30-44 hours and Sophomore 45-59 hours.

Description:

The principles of protein three-dimensional structure are examined.  The course is divided into "theoretical" and "application" sections.  In the theoretical section, general principles of protein structure are discussed in detail.  In the application section, the structural principles learned in the first part of the course are applied to particular protein systems.  Topics covered in the theoretical section of the course include:  covalent structure of proteins; protein secondary, tertiary and quaternary structure; physical forces influencing protein structure; protein surface areas and internal packing; internal motion in protein molecules; protein folding; comparison of protein primary and prediction of tertiary structures; and structural features of integral membrane proteins.

Students use computer graphics to visualize the principles of protein architecture that are described in class, to take quizzes, and to do homework assignments.

Instructor(s):

David A. Sanders

David A. Sanders
Dinesh Yernool

E-mail:

retrovir@purdue.edu; dyernool@purdue.edu

Textbook(s):

Text:  Protein Structure and Function      Required
Year/Edition:
ISBN Number:   0-87893-663-7
Author(s):  Petsko and Ringe
Publisher:  New Science Press/Sinauer

Course Format:

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